284319
1,8-二硝基芘
98%
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关于此项目
经验公式（希尔记法）:
C16H8N2O4
化学文摘社编号:
分子量:
292.25
UNSPSC Code:
12352100
PubChem Substance ID:
MDL number:
Assay:
98%
InChI
1S/C16H8N2O4/c19-17(20)13-7-3-9-1-2-10-4-8-14(18(21)22)12-6-5-11(13)15(9)16(10)12/h1-8H
SMILES string
[O-][N+](=O)c1ccc2ccc3ccc([N+]([O-])=O)c4ccc1c2c34
InChI key
BLYXNIHKOMELAP-UHFFFAOYSA-N
assay
98%
solubility
DMSO: soluble 2 mg/mL, clear, faintly yellow to yellow (faint green-yellow to very dark)
General description
The photodecomposition of environmental contaminant, 1,8-dinitropyrene via exposure to light (≥ 310nm) either in DMSO, or following coating onto silica has been investigated. 1,8-Dinitropyrene is a potent mutagenic component of diesel exhaust and air pollutant.
P J Harris et al.
Mutation research, 412(3), 323-331 (1998-05-26)
The abilities of brans from the cereals barley, oats, maize, rice, and wheat to adsorb in vitro the hydrophobic, environmental mutagen 1,8-dinitropyrene (DNP) were investigated using a mutagenicity assay. These brans were obtained from known cultivars using defined milling conditions
T Nohmi et al.
Molecular & general genetics : MGG, 247(1), 7-16 (1995-04-10)
Expression of the umuDC operon is required for UV and most chemical mutagenesis in Escherichia coli. The closely related species Salmonella typhimurium has two sets of umuDC-like operons, umuDCST on the chromosome and samAB on a 60-MDa cryptic plasmid. The
M A Belisario et al.
Bollettino della Societa italiana di biologia sperimentale, 71(1-2), 27-34 (1995-01-01)
Nitroarenes are environmental contaminants produced during incomplete combustion processes. It has been reported that nitroreduction, the most important pathway of nitroarene toxification, occurs mainly in the liver and intestine. In the present study we have shown that red cells also
Nitroarenes (selected) 1,8-dinitropyrene.
Report on carcinogens : carcinogen profiles, 11, III187-III188 (2004-01-01)
L R Ferguson et al.
Chemico-biological interactions, 95(3), 245-255 (1995-04-14)
Epidemiology and animal experiments indicate that dietary fibres protect against the development of colorectal cancer. However, insoluble dietary fibres appear to be more effective than soluble dietary fibres and one mechanism by which they may protect is by adsorbing dietary
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