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284572

4-氨基苯甲酰胺

Name: 4-氨基苯甲酰胺
Brand: ALDRICH

98%

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关于此项目

线性分子式:

H₂NC₆H₄CONH₂

化学文摘社编号:

2835-68-9

分子量:

136.15

NACRES:

NA.22

PubChem Substance ID:

24857167

UNSPSC Code:

12352100

EC Number:

220-612-3

MDL number:

MFCD00007999

Assay:

98%

Form:

solid

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属性

Quality Level

100

assay

98%

form

solid

mp

181-183 °C (lit.)

functional group

amide

SMILES string

NC(=O)c1ccc(N)cc1

InChI

1S/C7H8N2O/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H2,9,10)

InChI key

QIKYZXDTTPVVAC-UHFFFAOYSA-N

说明

Application

4-氨基苯甲酰胺作为多聚 ADP 核糖聚合酶 (PADPRP) 抑制剂，利用核酶多聚 ADP 核糖聚合酶 (PADPRP) 研究细胞毒性效应细胞对靶细胞的死亡作用。

pictograms

GHS07

signalword

Warning

hcodes

H319,H335

pcodes

P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Effect of inhibitors of poly(ADP-ribose)polymerase on the radiation response of HeLa S3 cells.

P Burgman et al.

Radiation research, 119(2), 380-386 (1989-08-01)

The purpose of this study was to investigate possible involvement of poly(ADP-ribosyl)ation reactions in X-ray-induced cell killing, repair of potentially lethal damage (PLD), and formation and repair of radiation-induced DNA damage. As tools we used the inhibitors of poly(ADP-ribose)polymerase, 3-aminobenzamide

Cell death protection by 3-aminobenzamide and other poly(ADP-ribose)polymerase inhibitors: different effects on human natural killer and lymphokine activated killer cell activities.

D Monti et al.

Biochemical and biophysical research communications, 199(2), 525-530 (1994-03-15)

The death of target cells by cytotoxic effector cells is a relevant biological phenomenon, where cells are activated and a very quick apoptotic program occurs. In order to test the hypothesis that the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP) plays a role

Interferon-gamma inhibits insulin release and induces cell death in the pancreatic beta-cell line INS-1 independently of nitric oxide production.

R Laffranchi et al.

Experimental cell research, 237(1), 217-222 (1998-01-07)

Interferon-gamma is among the cytokines which have been implicated as effector molecules of beta-cell destruction in autoimmune diabetes. Its mechanism of action is, however, largely unknown. In the present study rat pancreatic beta-cells, INS-1, were incubated with rat interferon-gamma (rIRN-gamma)

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全球贸易项目编号

货号	GTIN
284572-25G	04061826253564
284572-100G	04061838348456