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关于此项目
经验公式(希尔记法):
C10H14N2
化学文摘社编号:
分子量:
162.23
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥97%
Form:
liquid
InChI
1S/C10H14N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8,10,12H,1-2,5,7H2
SMILES string
C1CCC(NC1)c2cccnc2
InChI key
MTXSIJUGVMTTMU-UHFFFAOYSA-N
assay
≥97%
form
liquid
refractive index
n20/D 1.544 (lit.)
bp
96 °C/12 mmHg (lit.)
density
1.046 g/mL at 25 °C (lit.)
application(s)
agriculture
environmental
Quality Level
Gene Information
mouse ... Chrna1(11435), Chrna7(11441)
General description
Anabasine inhibited androstenedione conversion to estrogen in a dose-dependent manner.
Application
Anabasine, a tobacco alkaloid, was used as a biomarker of active tobacco use.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
199.4 °F - closed cup
flash_point_c
93 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Brenda B Suh-Lailam et al.
Journal of analytical toxicology, 38(7), 416-420 (2014-06-19)
Laboratory detection of nicotine exposure is important for establishing eligibility for organ transplant and elective surgery. Nicotine testing is also used to verify compliance with nicotine replacement therapies (NRT), smoking cessation programs and for life insurance purposes. Nicotine metabolites, such
R L Barbieri et al.
The Journal of clinical investigation, 77(6), 1727-1733 (1986-06-01)
Epidemiologic studies suggest that women who smoke have lower endogenous estrogen than nonsmokers. To explore the possible link between cigarette smoking and decreased endogenous estrogens, we have examined the effects of constituents of tobacco on estrogen production in human choriocarcinoma
J L Castorena et al.
Journal of toxicology. Clinical toxicology, 25(5), 429-435 (1987-01-01)
A young adult male was found dead in a field. No cause of death was apparent at autopsy, and the only positive toxicological finding was the presence of a nicotine-like alkaloid isolated from the liver. Anabasine, the major, highly toxic
N Mizrachi et al.
Journal of forensic sciences, 45(3), 736-741 (2000-06-16)
Death of a worker occurred after ingestion of unknown amounts of Nicotiana glauca G leaves. The leaves were cooked after having been mistakenly considered to be spices of a type which grow in Thailand. After ingestion, two Thai workers collapsed
Xu Xu et al.
Clinical chemistry, 50(12), 2323-2330 (2004-10-09)
Determination of nicotine metabolism/pharmacokinetics provides a useful tool for estimating uptake of nicotine and tobacco-related toxicants, for understanding the pharmacologic effects of nicotine and nicotine addiction, and for optimizing nicotine dependency treatment. We developed a sensitive method for analysis of
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