285536
5′-Deoxy-5′-(methylthio)adenosine
97%
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关于此项目
经验公式（希尔记法）:
C11H15N5O3S
化学文摘社编号:
分子量:
297.33
PubChem Substance ID:
UNSPSC Code:
41106305
Beilstein/REAXYS Number:
42420
MDL number:
产品名称
5′-Deoxy-5′-(methylthio)adenosine, 97%
SMILES string
CSCC1OC(C(O)C1O)n2cnc3c(N)ncnc23
InChI
1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)
InChI key
WUUGFSXJNOTRMR-UHFFFAOYSA-N
assay
97%
form
solid
法规信息
新产品
此项目有
Tobias J Erb et al.
Nature chemical biology, 8(11), 926-932 (2012-10-09)
Functional assignment of uncharacterized proteins is a challenge in the era of large-scale genome sequencing. Here, we combine in extracto NMR, proteomics and transcriptomics with a newly developed (knock-out) metabolomics platform to determine a potential physiological role for a ribulose-1,5-bisphosphate
Benjamin Pommerrenig et al.
The Plant cell, 23(5), 1904-1919 (2011-05-05)
The 5-methylthioadenosine (MTA) or Yang cycle is a set of reactions that recycle MTA to Met. In plants, MTA is a byproduct of polyamine, ethylene, and nicotianamine biosynthesis. Vascular transcriptome analyses revealed phloem-specific expression of the Yang cycle gene 5-METHYLTHIORIBOSE
Ivan Hemeon et al.
Analytical chemistry, 83(12), 4996-5004 (2011-05-07)
DNA (cytosine-5)-methyltransferases (DNMTs) catalyze the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the 5-position of cytosine residues and thereby silence transcription of regulated genes. DNMTs are important epigenetic targets. However, isolated DNMTs are weak catalysts and are difficult
Barbara Roe et al.
PloS one, 6(8), e23641-e23641 (2011-08-20)
Hepatitis C virus (HCV) is capable of disrupting different facets of lipid metabolism and lipids have been shown to play a crucial role in the viral life cycle. The aim of this study was to examine the effect HCV infection
Ishari Waduwara-Jayabahu et al.
Plant physiology, 158(4), 1728-1744 (2012-02-22)
5'-Methylthioadenosine (MTA) is the common by-product of polyamine (PA), nicotianamine (NA), and ethylene biosynthesis in Arabidopsis (Arabidopsis thaliana). The methylthiol moiety of MTA is salvaged by 5'-methylthioadenosine nucleosidase (MTN) in a reaction producing methylthioribose (MTR) and adenine. The MTN double
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