Quality Level
assay
98%
mp
148-150 °C (lit.)
functional group
amide
SMILES string
NC(=O)Cc1c[nH]c2ccccc12
InChI
1S/C10H10N2O/c11-10(13)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H2,11,13)
InChI key
ZOAMBXDOGPRZLP-UHFFFAOYSA-N
General description
吲哚-3-乙酰胺是一种生长素前体。
Application
吲哚-3-乙酰胺用于合成 [5.5.6.6] 二氮杂环乙烷骨架和吲哚-3-乙酸。
用于合成以下物质的反应物：
- 蛋白激酶 C 的 PET 显像剂
- 抗朊病毒病的潜在药物
- 蛋白激酶C（PKC）抑制剂双吲哚基马来酰亚胺IV
- 糖原合成酶激酶-3β (GSK-3β) 抑制剂
- CaMKIId 抑制剂
- VEGF 抑制剂
- JAK3 抑制剂
- NAD + 依赖性组蛋白去乙酰化酶抑制剂
- 人脂肪细胞脂肪酸结合蛋白抑制剂
- 细胞周期蛋白依赖性激酶抑制剂
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Rudy Maor et al.
Applied and environmental microbiology, 70(3), 1852-1854 (2004-03-10)
The plant pathogenic fungus Colletotrichum gloeosporioides f. sp. aeschynomene utilizes external tryptophan to produce indole-3-acetic acid (IAA) through the intermediate indole-3-acetamide (IAM). We studied the effects of tryptophan, IAA, and IAM on IAA biosynthesis in fungal axenic cultures and on
S Taliani et al.
Current medicinal chemistry, 16(26), 3359-3380 (2009-06-25)
The Translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor, is an 18 kDa mitochondrial protein primarily involved in steroid biosynthesis in both peripheral and glial cells. It has been extensively reported that TSPO regulates the rate-limiting translocation of
Elena Tsavkelova et al.
Fungal genetics and biology : FG & B, 49(1), 48-57 (2011-11-15)
The plant hormone indole-3-acetic acid (IAA) can be synthesized from tryptophan via the intermediate indole-3-acetamide (IAM). The two genes, IaaM (encoding tryptophan monooxygenase) and IaaH (encoding indole-3-acetamide hydrolase) that constitute the IAM pathway have been described in plant-associated bacteria. We
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 286281-1G | 04061826264676 |
| 286281-5G | 04061832841618 |