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286583

5-甲氧基色胺

Name: 5-甲氧基色胺
Brand: ALDRICH

97%

别名:

2-(5-甲氧基吲唑-3-基)乙胺, 3-(2-氨基乙基)-5-甲氧基吲哚, 5-MOT, 5-甲氧基吲哚-3-乙胺, NSC 56422, 去乙酰褪黑素

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关于此项目

经验公式（希尔记法）:

C₁₁H₁₄N₂O

化学文摘社编号:

608-07-1

分子量:

190.24

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24857245

EC Number:

210-153-7

Beilstein/REAXYS Number:

145587

MDL number:

MFCD00005662

Assay:

97%

Form:

solid

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属性

Quality Level

200

assay

97%

form

solid

drug control

Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

mp

121-123 °C (lit.)

functional group

amine

SMILES string

COc1ccc2[nH]cc(CCN)c2c1

InChI

1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3

InChI key

JTEJPPKMYBDEMY-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350), HTR2A(3356), HTR2C(3358)
rat ... Htr2a(29595), Htr2c(25187), Htr7(65032)

说明

General description

5-甲氧色胺（一种褪黑素的代谢物）在人角质细胞中应对紫外B（UVB）的保护性作用已得到研究。

Application

5-甲氧基色胺作为一种激动剂已被用于5-羟色胺1受体的药理作用研究中。

用于制备以下物质的反应物：

shishijimicin A的咔啉二糖结构域
褪黑激素类似物用于降低眼压
5-HT4受体配体
分选酶A和异柠檬酸裂解酶的抑制剂
用于治疗缺血/再灌注（I/R）损伤的治疗剂
Aurora和表皮生长因子受体激酶抑制剂
用于治疗人乳头瘤病毒感染的药剂
Manzamine类似物用于控制神经炎症和脑部感染
促炎细胞因子的抑制剂
Tacrine-melatonin杂合物作为阿尔茨海默病的多功能药物

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号	GTIN
286583-1G	04061826264751
286583-100MG	04061826264744