Merck
CN
All Photos(2)

286583

Sigma-Aldrich

5-甲氧基色胺

97%

All Photos(2)
Synonym(s):
2-(5-甲氧基吲唑-3-基)乙胺, 3-(2-氨基乙基)-5-甲氧基吲哚, 5-MOT, 5-甲氧基吲哚-3-乙胺, NSC 56422, 去乙酰褪黑素
Empirical Formula (Hill Notation):
C11H14N2O
CAS Number:
608-07-1
Molecular Weight:
190.24
Beilstein:
145587
EC 号:
210-153-7
MDL编号:
MFCD00005662
PubChem化学物质编号:
24857245
NACRES:
NA.22

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N-乙酰-5-羟色胺

≥99% (HPLC), powder

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Tryptamine ≥97%

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色胺

≥97%

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5-甲氧色胺 盐酸盐

crystalline

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O-甲氧基色胺

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3-(2-氨乙酸)吲哚 盐酸盐

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5-Hydroxy-L-tryptophan powder

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5-羟基L-色氨酸

powder

质量水平

200

测定

97%

形式

solid

mp

121-123 °C (lit.)

SMILES string

COc1ccc2[nH]cc(CCN)c2c1

InChI

1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3

InChI key

JTEJPPKMYBDEMY-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350) , HTR2A(3356) , HTR2C(3358)
rat ... Htr2a(29595) , Htr2c(25187) , Htr7(65032)

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一般描述

5-甲氧色胺（一种褪黑素的代谢物）在人角质细胞中应对紫外B（UVB）的保护性作用已得到研究。

应用

5-甲氧基色胺作为一种激动剂已被用于5-羟色胺1受体的药理作用研究中。
用于制备以下物质的反应物：
  • shishijimicin A的咔啉二糖结构域
  • 褪黑激素类似物用于降低眼压
  • 5-HT4受体配体
  • 分选酶A和异柠檬酸裂解酶的抑制剂
  • 用于治疗缺血/再灌注（I/R）损伤的治疗剂
  • Aurora和表皮生长因子受体激酶抑制剂
  • 用于治疗人乳头瘤病毒感染的药剂
  • Manzamine类似物用于控制神经炎症和脑部感染
  • 促炎细胞因子的抑制剂
  • Tacrine-melatonin杂合物作为阿尔茨海默病的多功能药物

包装

100 mg in glass insert
1, 25 g
无底玻璃瓶。内含物在插入的融合锥体内。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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