299154
L-甲硫氨酸-(甲基-13C,d3)
≥99 atom % 13C, ≥99 atom % D, ≥99% (CP)
别名:
SILAC Amino Acid
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关于此项目
线性分子式:
13CD3SCH2CH2CH(NH2)CO2H
化学文摘社编号:
分子量:
153.22
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Isotopic purity:
≥99 atom % 13C
≥99 atom % D
≥99 atom % D
Assay:
≥99% (CP)
Mass shift:
M+4
Form:
powder
产品名称
L-甲硫氨酸-(甲基-13C,d3), ≥99 atom % 13C, ≥99 atom % D, ≥99% (CP)
InChI
1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1/i1+1D3
SMILES string
[2H][13C]([2H])([2H])SCC[C@H](N)C(O)=O
InChI key
FFEARJCKVFRZRR-ZIHWZSJBSA-N
isotopic purity
≥99 atom % 13C
≥99 atom % D
assay
≥99% (CP)
form
powder
optical activity
[α]25/D +23.1°, c = 1 in 1 M HCl
technique(s)
protein expression: suitable
mp
284 °C (dec.) (lit.)
mass shift
M+4
Quality Level
Application
用于通过稳定表位同位素标记 (SITE) 方法，鉴定疫苗开发中病毒诱导的肽。
Packaging
这种产品可以散装供应，并可按需包装。有关定价、供货和包装的信息，请联系稳定同位素客户服务。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Martin Bachman et al.
Nature chemical biology, 11(8), 555-557 (2015-06-23)
5-Formylcytosine (5fC) is a rare base found in mammalian DNA and thought to be involved in active DNA demethylation. Here, we show that developmental dynamics of 5fC levels in mouse DNA differ from those of 5-hydroxymethylcytosine (5hmC), and using stable
Hugo D Meiring et al.
Molecular & cellular proteomics : MCP, 5(5), 902-913 (2006-01-25)
Identification of peptides presented in major histocompatibility complex (MHC) class I molecules after viral infection is of strategic importance for vaccine development. Until recently, mass spectrometric identification of virus-induced peptides was based on comparative analysis of peptide pools isolated from
Valeria Spadotto et al.
Nucleic acids research, 48(1), 96-115 (2019-11-30)
MicroRNA (miRNA) biogenesis is a tightly controlled multi-step process operated in the nucleus by the activity of the Microprocessor and its associated proteins. Through high resolution mass spectrometry (MS)- proteomics we discovered that this complex is extensively methylated, with 84
Daniele Musiani et al.
Science signaling, 12(575) (2019-04-04)
Protein arginine methyltransferases (PRMTs) catalyze arginine methylation on both chromatin-bound and cytoplasmic proteins. Accumulating evidence supports the involvement of PRMT5, the major type II PRMT, in cell survival and differentiation pathways that are important during development and in tumorigenesis. PRMT5
Daniele Musiani et al.
Cell reports, 30(4), 1208-1222 (2020-01-30)
Protein arginine methyltransferase 1 (PRMT1) is overexpressed in various human cancers and linked to poor response to chemotherapy. Various PRMT1 inhibitors are currently under development; yet, we do not fully understand the mechanisms underpinning PRMT1 involvement in tumorigenesis and chemoresistance.
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