301469
(S)-(+)-5-氧代-2-四氢呋喃羧酸
98%
别名:
(S)-γ-羧基-γ-丁内酯, (S)-5-氧代四氢-2-呋喃羧酸
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C5H6O4
化学文摘社编号:
分子量:
130.10
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1424498
产品名称
(S)-(+)-5-氧代-2-四氢呋喃羧酸, 98%
InChI
1S/C5H6O4/c6-4-2-1-3(9-4)5(7)8/h3H,1-2H2,(H,7,8)/t3-/m0/s1
SMILES string
OC(=O)[C@@H]1CCC(=O)O1
InChI key
QVADRSWDTZDDGR-VKHMYHEASA-N
assay
98%
optical activity
[α]20/D +14°, c = 5 in methanol
optical purity
ee: 99% (GLC)
bp
150-155 °C/0.2 mmHg (lit.)
mp
71-73 °C (lit.)
functional group
carboxylic acid
ester
Application
用于制备对肿瘤细胞具有细胞毒活性的 municatacin 类似物。
(S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid may be used as a ligand to form water-soluble silver(I) complexes by reacting with silver oxide. These complexes show good antibacterial and antifungal activities. It may also be used a chiral resolving agent during the multi-step synthesis of phosphatidylinositol 3,5-bisphosphate [PtdIns(3,5)P2].
General description
(S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid is a chiral derivatizing agent for alcohols.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Synthesis and crystal structure of three silver (I) complexes with (S)-(+)-5-oxo-2-tetrahydrofurancarboxylic acid (S-Hothf) and its isomeric forms (R-Hothf and R, S-Hothf) showing wide spectra of effective antibacterial and antifungal activities. ....
Nomiya K, et al.
J. Chem. Soc., Dalton Trans., 8, 1343-1348 (2000)
Figadere, B.
Tetrahedron Letters, 32, 7539-7539 (1991)
Hongde Li et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(6), 1353-1358 (2017-01-25)
L-2-hydroxyglutarate (L-2HG) has emerged as a putative oncometabolite that is capable of inhibiting enzymes involved in metabolism, chromatin modification, and cell differentiation. However, despite the ability of L-2HG to interfere with a broad range of cellular processes, this molecule is
l-a-Phosphatidyl-d-myo-inositol 3, 5-bisphosphate: total synthesis of a new inositol phospholipid via myo-inositol orthoacetate.
Riley AM and Potter BVL
Tetrahedron Letters, 39(37), 6769-6772 (1998)
Chaitanya A Kulkarni et al.
eLife, 9 (2020-08-17)
Alkb homolog 7 (ALKBH7) is a mitochondrial α-ketoglutarate dioxygenase required for DNA alkylation-induced necrosis, but its function and substrates remain unclear. Herein, we show ALKBH7 regulates dialdehyde metabolism, which impacts the cardiac response to ischemia-reperfusion (IR) injury. Using a multi-omics
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持