30681
L-4-羟脯氨酸甲酯 盐酸盐
≥98.0% (GC)
别名:
(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester hydrochloride, trans-4-Hydroxyproline methyl ester hydrochloride
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关于此项目
经验公式（希尔记法）:
C6H11NO3 · HCl
化学文摘社编号:
分子量:
181.62
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
4716932
产品名称
L-4-羟脯氨酸甲酯 盐酸盐, ≥98.0% (GC)
InChI
1S/C6H11NO3.ClH/c1-10-6(9)5-2-4(8)3-7-5;/h4-5,7-8H,2-3H2,1H3;1H/t4-,5+;/m1./s1
SMILES string
Cl.COC(=O)[C@@H]1C[C@@H](O)CN1
InChI key
KLGSHNXEUZOKHH-JBUOLDKXSA-N
assay
≥98.0% (GC)
form
solid
reaction suitability
reaction type: solution phase peptide synthesis
application(s)
peptide synthesis
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Emily M Christensen et al.
The Journal of biological chemistry, 295(52), 18316-18327 (2020-10-29)
Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reducing Δ1-pyrroline-5-carboxylate (P5C) to proline through the oxidation of NAD(P)H. Many cancers alter their proline metabolism by up-regulating the proline cycle and proline biosynthesis, and knockdowns of
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