产品名称
1-苯基-2-吡咯烷酮, 99%
InChI key
JMVIVASFFKKFQK-UHFFFAOYSA-N
InChI
1S/C10H11NO/c12-10-7-4-8-11(10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2
SMILES string
O=C1CCCN1c2ccccc2
assay
99%
form
solid
bp
123 °C/0.2 mmHg (lit.)
mp
67-69 °C (lit.)
Quality Level
General description
A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Mark S Duxbury et al.
Biochemical and biophysical research communications, 313(4), 992-997 (2004-01-07)
Blebbistatin is a novel 1-phenyl-2-pyrrolidinone derivative capable of inhibiting non-muscle myosin II activity with a high degree of specificity. We examined the effects of blebbistatin on pancreatic adenocarcinoma cellular migration, invasion, adhesion, and spreading. Blebbistatin dose-dependently inhibited cellular migration and
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