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324345

4-硝基-1,8-萘二酸酐

Name: 4-硝基-1,8-萘二酸酐
Brand: ALDRICH

95%

别名:

4-硝基-1,8-萘二甲酸酐

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关于此项目

经验公式（希尔记法）:

C₁₂H₅NO₅

化学文摘社编号:

6642-29-1

分子量:

243.17

UNSPSC Code:

12162002

NACRES:

NA.23

PubChem Substance ID:

24859437

EC Number:

229-659-4

Beilstein/REAXYS Number:

237909

MDL number:

MFCD00013446

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属性

Quality Level

100

assay

95%

mp

226-229 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc2C(=O)OC(=O)c3cccc1c23

InChI

1S/C12H5NO5/c14-11-7-3-1-2-6-9(13(16)17)5-4-8(10(6)7)12(15)18-11/h1-5H

InChI key

LKOZHLXUWUBRDK-UHFFFAOYSA-N

说明

General description

4-Nitro-1,8-naphthalic anhydride is a yellow crystalline nitrocompound widely used in the field of dye synthesis and cellular imaging.

Application

4-Nitro-1,8-naphthalic anhydride can be used:

As a precursor to synthesize N-phenyl-amino-1,8-naphthalimide based fluorescent chemosensor to detect nitro-antibiotics at ppb level.
As a building block to synthesize shape memory polymers due to its ability to undergo Diels-Alder reaction
As a fluorochrome substrate for nitrogen reductase for noninvasive hypoxia imaging in cancer detection.
As a precursor to synthesize amphiphilic naphthalimide dyes with good color brilliancy.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Spectral Characteristics and Sensor Ability of a New 1,8-Naphthalimide and Its Copolymer with Styrene.

Desislava Staneva et al.

Sensors (Basel, Switzerland), 20(12) (2020-06-25)

In this study, a novel 6-(allylamino)-2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (NI3) was synthesized and characterized. Its copolymer with styrene was also obtained. The photophysical characteristics of NI3 were investigated in organic solvents and the results were compared with those of its structural analogue, 2-allyl-6-((2-(dimethylamino)ethyl)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Discriminative fluorescent sensing of nitro-antibiotics at ppb level using N-phenyl-amino-1,8-naphthalimides chemosensors

Ananthu Shanmughan, et al.

Results in Chemistry, 4, 100546-100546 (2022)

A Lysosome-Targeting Fluorescence Off-On Probe for Imaging of Nitroreductase and Hypoxia in Live Cells.

Jin Zhou et al.

Chemistry, an Asian journal, 11(19), 2719-2724 (2016-02-09)

A lysosome-targeting fluorescent off-on probe has been developed by one-step synthesis for detecting lysosomal nitroreductase and hypoxia. The probe is constructed by incorporating morpholine (a lysosome-targeting unit) into 4-nitro-1,8-naphthalimide (as a fluorochrome and specific substrate for nitroreductase), and the detection

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全球贸易项目编号

货号	GTIN
324345-5G	04061826710821
324345-25G	04061833014042