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Merck
CN

327190

Sigma-Aldrich

亚硝酸异丁酯

95%

别名:

2-亚硝酸甲丙酯

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关于此项目

线性分子式:
(CH3)2CHCH2ONO
化学文摘社编号:
分子量:
103.12
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

95%

表单

liquid

折射率

n20/D 1.373 (lit.)

沸点

66-67 °C (lit.)

密度

0.87 g/mL at 25 °C (lit.)

官能团

O-nitroso
nitroso

储存温度

2-8°C

SMILES字符串

CC(C)CON=O

InChI

1S/C4H9NO2/c1-4(2)3-7-5-6/h4H,3H2,1-2H3

InChI key

APNSGVMLAYLYCT-UHFFFAOYSA-N

一般描述

亚硝酸异丁酯广泛用作室内除臭剂。这是一种流行的娱乐药物。

应用

亚硝酸异丁酯用于研究吸入剂诱导的免疫毒性。

警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2 - Muta. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

-5.8 °F - closed cup

闪点(°C)

-21 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A J Davies et al.
Eye (London, England), 26(11), 1479-1486 (2012-10-20)
Poppers are a recreational substance of abuse belonging to the alkyl nitrite family of compounds. In the United Kingdom, where they are legal to purchase but illegal to sell for human consumption, 10% of the general population have tried them.
T Jansen et al.
Acta anaesthesiologica Scandinavica, 47(10), 1300-1301 (2003-11-18)
A young man was accidentally intoxicated with isobutyl nitrite by a threefold lethal dose. Due to nitrites' ability to change hemoglobine into methemoglobine the patient showed signs of severe hypoxia, which could not be treated by conventional means. Therefore the
L S Soderberg et al.
International journal of immunopharmacology, 22(2), 151-157 (2000-02-24)
Nitrite inhalant abuse has been correlated epidemiologically with HIV seropositivity and with Kaposi's sarcoma. Using a mouse model, we have shown that inhaled isobutyl nitrite caused anemia and severely depressed immunity. In the present study, we showed that both isobutyl
[Methemoglobinemia due to ingestion of isobutyl nitrite ('poppers')].
W G Zijlstra
Nederlands tijdschrift voor geneeskunde, 147(11), 522-523 (2003-04-08)
J Lindenmann et al.
Inhalation toxicology, 18(13), 1047-1049 (2006-09-13)
Methemoglobinemia usually results from exposure to oxidizing substances such as nitrates or nitrites. Iron within hemoglobin is oxidized from the ferrous (Fe2+) state to the ferric (Fe3+) state, resulting in the inability to transport oxygen and carbon dioxide. Clinically, this

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