质量水平
方案
95%
表单
liquid
折射率
n20/D 1.373 (lit.)
沸点
66-67 °C (lit.)
密度
0.87 g/mL at 25 °C (lit.)
官能团
O-nitroso
nitroso
储存温度
2-8°C
SMILES字符串
CC(C)CON=O
InChI
1S/C4H9NO2/c1-4(2)3-7-5-6/h4H,3H2,1-2H3
InChI key
APNSGVMLAYLYCT-UHFFFAOYSA-N
一般描述
亚硝酸异丁酯广泛用作室内除臭剂。这是一种流行的娱乐药物。
应用
亚硝酸异丁酯用于研究吸入剂诱导的免疫毒性。
警示用语：
Danger
危险分类
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2 - Muta. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
-5.8 °F - closed cup
闪点(°C)
-21 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
A J Davies et al.
Eye (London, England), 26(11), 1479-1486 (2012-10-20)
Poppers are a recreational substance of abuse belonging to the alkyl nitrite family of compounds. In the United Kingdom, where they are legal to purchase but illegal to sell for human consumption, 10% of the general population have tried them.
Steven G Turowski et al.
The AAPS journal, 9(3), E298-E305 (2007-10-06)
We examined the effects of acute isobutyl nitrite (ISBN) exposure on the activity of several hepatic enzymes. Two strains of adult male mice (Balb/c and C57BL/6) were exposed to 900 ppm ISBN or ambient air for 45 minutes. The enzyme
Doanh C Tran et al.
Biochemical and biophysical research communications, 310(2), 439-445 (2003-10-03)
Inhalant nitrites are drugs of abuse that have been shown to enhance tumor growth rate in mice and are epidemiologically linked to an increased risk of Kaposi's sarcoma. Because nitrites produce nitric oxide, we hypothesized that their toxicological effects might
L S Soderberg et al.
International journal of immunopharmacology, 22(2), 151-157 (2000-02-24)
Nitrite inhalant abuse has been correlated epidemiologically with HIV seropositivity and with Kaposi's sarcoma. Using a mouse model, we have shown that inhaled isobutyl nitrite caused anemia and severely depressed immunity. In the present study, we showed that both isobutyl
J Lindenmann et al.
Inhalation toxicology, 18(13), 1047-1049 (2006-09-13)
Methemoglobinemia usually results from exposure to oxidizing substances such as nitrates or nitrites. Iron within hemoglobin is oxidized from the ferrous (Fe2+) state to the ferric (Fe3+) state, resulting in the inability to transport oxygen and carbon dioxide. Clinically, this
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