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Merck
CN

329061

2-巯基吡啶-N-氧化物 钠盐

96-106%

别名:

1-Oxo-2-pyridinethiol sodium salt, 2-Pyridinethiol N-oxide sodium salt, Sodium (2-pyridylthio-1-oxide), Sodium 2-mercaptopyridine 1-oxide, Sodium 2-mercaptopyridine N-oxide

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关于此项目

经验公式(希尔记法):
C5H4NNaOS
化学文摘社编号:
分子量:
149.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
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产品名称

2-巯基吡啶-N-氧化物 钠盐, 96-106%

InChI

1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1

SMILES string

O.[O-][n+]1ccccc1S[Na]

InChI key

WNGMMIYXPIAYOB-UHFFFAOYSA-M

assay

96-106%

solubility

water: soluble 0.5 g/10 mL, clear, colorless to light yellow

Quality Level

Application

2-巯基吡啶-N-氧化物的化学作用,请参见 Aldrichimica Acta

General description

2-Mercaptopyridine N-oxide acts as labelling agent during indium-111 labelling of human platelets. It acts as bioactive ligand and forms palladium and platinum complexes, which were tested as potential antitrypanosomal agents.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

target_organs

Nervous system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Y Isaka et al.
European journal of nuclear medicine, 18(5), 326-331 (1991-01-01)
Human platelets were labelled in the absence or presence of plasma using indium-111 labelled oxine sulphate, tropolone or 2-mercaptopyridine-N-oxide (MPO). Under in vitro and in vivo conditions, platelet functions were evaluated by measuring their aggregability, survival, recovery and early distribution.
Marisol Vieites et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 13(5), 723-735 (2008-03-07)
In the search for new therapeutic tools against Chagas disease (American trypanosomiasis) palladium and platinum complexes of the bioactive ligand pyridine-2-thiol N-oxide were exhaustively characterized and evaluated in vitro. Both complexes showed high in vitro growth inhibition activity (IC(50) values
Aldrichimica Acta, 20, 35-35 (1987)

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