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文件

332623

三乙酰基-β-环糊精

Name: 三乙酰基-β-环糊精
Brand: ALDRICH

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所有图片(1)

别名:

三乙酰-β-环式糊精

经验公式（希尔记法）:

C₈₄H₁₁₂O₅₆

CAS号:

23739-88-0

分子量:

2017.75

MDL编号:

MFCD00074981

PubChem化学物质编号:

329754482

NACRES:

NA.22

形式

powder

质量水平

100

旋光性

[α]25/D +125°, c = 1 in chloroform

mp

204-206 °C (lit.)

SMILES string

CC(=O)OC[C@H]1O[C@@H]2O[C@@H]3[C@@H](COC(C)=O)O[C@H](O[C@@H]4[C@@H](COC(C)=O)O[C@H](O[C@@H]5[C@@H](COC(C)=O)O[C@H](O[C@@H]6[C@@H](COC(C)=O)O[C@H](O[C@@H]7[C@@H](COC(C)=O)O[C@H](O[C@@H]8[C@@H](COC(C)=O)O[C@H](O[C@H]1[C@@H](OC(C)=O)[C@@H]2OC(C)=O)[C@@H](OC(C)=O)[C@@H]8OC(C)=O)[C@@H](OC(C)=O)[C@@H]7OC(C)=O)[C@@H](OC(C)=O)[C@@H]6OC(C)=O)[C@@H](OC(C)=O)[C@@H]5OC(C)=O)[C@@H](OC(C)=O)[C@@H]4OC(C)=O)[C@@H](OC(C)=O)[C@@H]3OC(C)=O

InChI

1S/C84H112O56/c1-29(85)106-22-50-57-64(113-36(8)92)71(120-43(15)99)78(127-50)135-58-51(23-107-30(2)86)129-80(73(122-45(17)101)65(58)114-37(9)93)137-60-53(25-109-32(4)88)131-82(75(124-47(19)103)67(60)116-39(11)95)139-62-55(27-111-34(6)90)133-84(77(126-49(21)105)69(62)118-41(13)97)140-63-56(28-112-35(7)91)132-83(76(125-48(20)104)70(63)119-42(14)98)138-61-54(26-110-33(5)89)130-81(74(123-46(18)102)68(61)117-40(12)96)136-59-52(24-108-31(3)87)128-79(134-57)72(121-44(16)100)66(59)115-38(10)94/h50-84H,22-28H2,1-21H3/t50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71+,72+,73+,74+,75+,76+,77?,78-,79-,80-,81-,82-,83-,84-/m1/s1

InChI key

NOPKOJDDVCBPTP-URXASQAJSA-N

一般描述

Triacetyl-β-cyclodextrin, a water-insoluble derivative of cyclodextrin typically formed by the substitution of a hydroxyl group of the parent compound with maleic anhydride (−OCOCH₃), has been proposed to act as a sustained release carrier for some pharmaceutical compounds.

应用

Invovled in studies of:

Controlled drug release of an inclusion complex
Biocompatible excipients for solubilization and deaggregation of cobalt bis(dicarbollide) derivatives in water
Extraction of aromatic amino acids
Emulsifiers
Polymerization initiation of cyclic esters
Sustained release matrix tablets

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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索取COA

Effect of the hydrophobic nature of triacetyl-beta-cyclodextrin on the complexation with nicardipine hydrochloride: physicochemical and dissolution properties of the kneaded and spray-dried complexes.

Catarina Marques Fernandes et al.

Chemical & pharmaceutical bulletin, 50(12), 1597-1602 (2002-12-25)

The inclusion ability of triacetyl-beta-cyclodextrin (TAbetaCD), a hydrophobic cyclodextrin (CD) derivative was examined, using nicardipine hydrochloride (NC) as model drug. The binary compounds were prepared in a 1 : 1 molar ratio by the kneading and the spray-drying techniques. In

Eighteenth IAPRI World Packaging Conference

Eighteen Steps to a Healthy Life (2012)

Nonaqueous capillary electrophoresis equipped with amperometric detection for analysis of chlorinated phenolic compounds.

J H Luong et al.

Journal of chromatography. A, 864(2), 323-333 (2000-02-11)

Nonaqueous capillary electrophoresis (NACE) equipped with amperometric detection has been developed for separation and detection of an 11-member model mixture of chlorinated phenolic compounds. With triacetyl-beta-cyclodextrin (TACD) as a novel selectivity selector, acetonitrile proved to be an excellent solvent for

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