333328
6-乙氧基-2-苯并噻唑磺酰胺
97%
别名:
6-乙氧基-2-苯并噻唑磺酰胺, 依索唑胺
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关于此项目
经验公式（希尔记法）:
C9H10N2O3S2
化学文摘社编号:
分子量:
258.32
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-199-5
MDL number:
Assay:
97%
Form:
solid
assay
97%
form
solid
mp
190-193 °C (lit.)
SMILES string
CCOc1ccc2nc(sc2c1)S(N)(=O)=O
InChI
1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)
InChI key
OUZWUKMCLIBBOG-UHFFFAOYSA-N
Gene Information
human ... CA1(759), CA12(771), CA13(377677), CA14(23632), CA2(760), CA3(761), CA4(762), CA5A(763), CA5B(11238), CA6(765), CA7(766), CA9(768)
mouse ... Car5a(12352)
General description
6-乙氧基-2-苯并噻唑磺酰胺是一种膜渗透性碳酸酐酶抑制剂，已在正常白兔中对其眼部分布和药理学进行了研究。在体外引起抑制胰岛素降解 。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Holger M Becker et al.
The Journal of biological chemistry, 282(18), 13508-13521 (2007-03-14)
Several acid/base-coupled membrane transporters, such as the electrogenic sodium-bicarbonate cotransporter (NBCe1), have been shown to bind to different carbonic anhydrase isoforms to create a "transport metabolon." We have expressed NBCe1 derived from human kidney in oocytes of Xenopus leavis and
Studies of the effect of carbutamide on glucose-6-phosphatase.
C A KUETHER et al.
Diabetes, 6(1), 23-25 (1957-01-01)
Jatinder Kaur et al.
Journal of medicinal chemistry, 63(17), 9540-9562 (2020-08-14)
Vancomycin-resistant enterococci (VRE) are the second leading cause of hospital-acquired infections (HAIs) attributed to a drug-resistant bacterium in the United States, and resistance to the frontline treatments is well documented. To combat VRE, we have repurposed the FDA-approved carbonic anhydrase
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 333328-1G | 04061826732434 |