334642
双(环戊二烯基)二氯化钒(IV)
95%
别名:
Di-π-Cyclopentadienylvanadium dichloride, Dichlorobis(cyclopentadienyl)vanadium, Dichlorovanadocene, Vanadocene dichloride
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关于此项目
经验公式（希尔记法）:
C10H10Cl2V
化学文摘社编号:
分子量:
252.03
UNSPSC Code:
12352300
PubChem Substance ID:
EC Number:
235-150-8
MDL number:
assay
95%
form
solid
reaction suitability
core: vanadium, reagent type: catalyst
storage temp.
2-8°C
SMILES string
Cl[V]Cl.[CH]1[CH][CH][CH][CH]1.[CH]2[CH][CH][CH][CH]2
InChI
1S/2C5H5.2ClH.V/c2*1-2-4-5-3-1;;;/h2*1-5H;2*1H;/q;;;;+2/p-2
InChI key
MDWJZZZKWHLMQP-UHFFFAOYSA-L
Application
Uses:
- Potential pharmacological compound for cancer treatment
- Catalyst for solvent free, room temperature preparation of vicinal aminoalcohols as fungistatic agents
- Catalyst fot oligomerization reactions via the Aufbau propagation reaction
- Catalyst for aqueous polymerization reactions using oxygen as a cocatalyst
- Catalyst for dl-selective pinacol-type coupling reactions
- Affector of crystal growth of calcium carbonate
- Inhibitor of human topoisomerase II enzyme with antitumor activity
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
P Köpf-Maier et al.
Chemico-biological interactions, 44(3), 317-328 (1983-06-01)
The intracellular distribution patterns of the metal atoms titanium and vanadium after in vivo as well as in vitro treatment of Ehrlich ascites tumor with the antitumor agents titanocene dichloride (TDC) or vanadocene dichloride (VDC) have been investigated by use
P Köpf-Maier
Journal of cancer research and clinical oncology, 103(2), 145-164 (1982-01-01)
Light-microscopic and ultrastructural alteration patterns are investigated after in vivo treatment of EAT with the cytostatic agents VDC and TC. Both substances induce mitotic aberrations, e.g., pyknotic metaphases, lagging chromosomes during anaphase, and multipolar mitotic figures. The appearance of mononucleate
J H Toney et al.
Chemico-biological interactions, 56(1), 45-54 (1985-12-17)
The biodistribution and pharmacokinetics of vanadium following i.p. administration of vanadocene dichloride (VDC), a representative of a new class of organometallic anticancer agents, is reported for Strain A mice. A convenient flameless atomic absorption spectroscopic assay is described and is
O J D'Cruz et al.
Biology of reproduction, 58(6), 1515-1526 (1998-06-12)
We have used computer-assisted sperm analysis (CASA) to evaluate the spermicidal activity of 8 metallocene dihalides (vanadocene dichloride [VDC], titanocene dichloride [TDC], zirconocene dichloride [ZDC], molybdocene dichloride [MDC], hafnocene dichloride [HDC], vanadocene dibromide [VDB], bis[methylcyclopentadienyl] vanadium dichloride [VMDC], and vanadocene
P Köpf-Maier et al.
Journal of cancer research and clinical oncology, 102(1), 21-30 (1981-01-01)
The influence of an in vivo treatment with optimally tumor-inhibiting doses of cis-diamminedichloroplatinum(II) (DDP), titanocene dichloride (TDC), and vanadocene dichloride (VDC) on the DNA distribution pattern, determined by pulse-cytophotometry, and on the mitotic activity of EAT cells is investigated. Whereas
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