335673
1-十二烷基-2-吡咯烷酮
99%
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关于此项目
经验公式（希尔记法）:
C16H31NO
化学文摘社编号:
分子量:
253.42
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
403-730-1
MDL number:
Assay:
99%
Form:
viscous liquid
产品名称
1-十二烷基-2-吡咯烷酮, 99%
InChI key
NJPQAIBZIHNJDO-UHFFFAOYSA-N
InChI
1S/C16H31NO/c1-2-3-4-5-6-7-8-9-10-11-14-17-15-12-13-16(17)18/h2-15H2,1H3
SMILES string
CCCCCCCCCCCCN1CCCC1=O
assay
99%
form
viscous liquid
refractive index
n20/D 1.466 (lit.)
bp
202-205 °C/11 mmHg (lit.)
density
0.89 g/mL at 25 °C (lit.)
Quality Level
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Application
1-十二烷基-2-吡咯烷酮用于通过块状 MoS2 粉末的液相剥离来制备几层的二硫化钼（MoS2）薄片。
General description
1-十二烷基-2-吡咯烷酮是 N-烷基内酰胺，据报道其被 LiH3BNMe2 还原为相应的胺。它是潜在的褪黑激素特异性化学渗透促进剂。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Skin Corr. 1B - Skin Sens. 1
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
S Sato et al.
Chemical & pharmaceutical bulletin, 46(5), 831-836 (1998-06-11)
The enhancing effects of N-dodecyl-2-pyrrolidone (NDP) on the percutaneous absorption of doxifluridine (DOX), 5-fluorouracil (5-FU), tegafur (TEG) and carmofur (CAR) were examined using an in vitro penetration technique and rat skin. Phosphate buffered isotonic saline (PBS), propylene glycol (PG) and
Andrew Winchester et al.
ACS applied materials & interfaces, 6(3), 2125-2130 (2014-01-22)
We report on the electrochemical charge storage behavior of few-layered flakes of molybdenum disulfide (MoS2) obtained by liquid phase exfoliation of bulk MoS2 powder in 1-dodecyl-2-pyrrolidinone. The specific capacitances of the exfoliated flakes obtained using a 6 M KOH aqueous
Vijay Krishna Rachakonda et al.
Pharmaceutical research, 25(11), 2697-2704 (2008-08-07)
A novel technique is presented for identifying potential chemical penetration enhancers (CPEs) based on changes in the electrical resistance of skin. Specifically, a multi-well resistance chamber was designed and constructed to facilitate more rapid determination of the effect of CPEs
Srinivas S Godavarthy et al.
Journal of pharmaceutical sciences, 98(11), 4085-4099 (2009-08-22)
One promising way to breach the skin's natural barrier to drugs is by the application of chemicals called penetration enhancers. However, identifying potential enhancers is difficult and time consuming. We have developed a virtual screening algorithm for generating potential chemical
J Nakamura et al.
Journal of pharmacobio-dynamics, 14(1), 1-8 (1991-01-01)
Anticonvulsant activity, degradation into gamma-aminobutyric acid (GABA), and concentration in brain of 1-dodecanoyl-2-pyrrolidinone (I), a lipophilic derivative of a lactam of GABA, were compared with those of N-dodecanoyl GABA (II) and 1-dodecyl-2-pyrrolidinone (III) to get information about their pharmacological mechanisms.
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