质量水平
方案
98%
表单
liquid
折射率
n20/D 1.494 (lit.)
沸点
139 °C/0.5 mmHg (lit.)
密度
1.047 g/mL at 25 °C (lit.)
官能团
ether
ketone
SMILES字符串
CCCCOC1=C(OCCCC)C(=O)C1=O
InChI
1S/C12H18O4/c1-3-5-7-15-11-9(13)10(14)12(11)16-8-6-4-2/h3-8H2,1-2H3
InChI key
XBRWELTXMQSEIN-UHFFFAOYSA-N
一般描述
3,4-二丁氧基-3-环丁烯-1,2-二酮是方酸的二烷基酯。
应用
3,4-二丁氧基-3-环丁烯-1,2-二酮用于合成新型半方酸染料，可用于在水性介质中进行高选择性Hg2+传感。它也用于合成3-丁氧基-4-(1,3,3-三甲基-2,3-二氢-1H-2-吲哚基亚甲基)-3-环丁烯-1,2-二酮的中间体方酸染料。
警示用语：
Warning
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Amy J McMichael et al.
Dermatology nursing, 16(4), 333-336 (2004-10-09)
Though many therapies exist for alopecia areata, one of the most unique is topical sensitization. By altering the pathogenic inflammatory response with few side effects, sensitizers offer an attractive treatment option for many patients with alopecia areata, including those who
Molecular and crystal structure of 3-butoxy-4-(1, 3, 3-trimethyl-2, 3-dihydro-1H-2-indolylidenemethyl)-3-cyclobutene-1, 2-dione and its thio analog.
Shishkina SV, et al.
Journal of Structural Chemistry, 46(1), 154-158 (2005)
F Dall'oglio et al.
The Journal of dermatological treatment, 16(1), 10-14 (2005-05-18)
Severe alopecia areata (AA) may have a chronic relapsing course and is often resistant to current treatments. The aim of our study was to evaluate whether topical immunotherapy with squaric acid dibutylester (SADBE) is able to improve the course of
Cutaneous lymphoid hyperplasia related to squaric acid dibutyl ester.
Eric A Millican et al.
Journal of the American Academy of Dermatology, 65(1), 230-232 (2011-06-18)
Eileen Tan et al.
International journal of dermatology, 41(11), 748-753 (2002-11-28)
Alopecia areata is believed to be an autoimmune condition with a worldwide occurrence. It usually presents as patchy, nonscarring hair loss. There is a paucity of clinical data in Asians. To study the epidemiology, clinical aspects, associations, and treatment of
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