339792
3,4-二丁氧基-3-环丁烯-1,2-二酮
98%
别名:
方酸二正丁酯
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关于此项目
线性分子式:
[CH3(CH2)3O]2C4(=O)2
化学文摘社编号:
分子量:
226.27
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
liquid
InChI
1S/C12H18O4/c1-3-5-7-15-11-9(13)10(14)12(11)16-8-6-4-2/h3-8H2,1-2H3
SMILES string
CCCCOC1=C(OCCCC)C(=O)C1=O
InChI key
XBRWELTXMQSEIN-UHFFFAOYSA-N
assay
98%
form
liquid
refractive index
n20/D 1.494 (lit.)
bp
139 °C/0.5 mmHg (lit.)
density
1.047 g/mL at 25 °C (lit.)
functional group
ether, ketone
Quality Level
General description
3,4-二丁氧基-3-环丁烯-1,2-二酮是方酸的二烷基酯。
Application
3,4-二丁氧基-3-环丁烯-1,2-二酮用于合成新型半方酸染料，可用于在水性介质中进行高选择性Hg2+传感。它也用于合成3-丁氧基-4-(1,3,3-三甲基-2,3-二氢-1H-2-吲哚基亚甲基)-3-环丁烯-1,2-二酮的中间体方酸染料。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Treatment of alopecia areata in children.
Niyati Mukherjee et al.
Pediatric annals, 38(7), 388-395 (2009-08-19)
Yayoi Shimaoka et al.
The Journal of dermatology, 35(3), 151-153 (2008-03-19)
A 57-year-old Japanese male patient with an 18-year history of discoid lupus erythematosus (DLE) presented with alopecia on his scalp, and was clinically diagnosed to have alopecia areata. He was started on topical immunotherapy with squaric acid dibutylester (SADBE) for
Shigeki Inui et al.
The Journal of dermatology, 36(6), 323-327 (2009-06-09)
To study the effect of fexofenadine on extensive alopecia areata (AA), we evaluated retrospectively 121 patients with AA having alopecia in more than 50% of the scalp and followed them for at least 6 months. Patients were treated by immunotherapy
Synthesis of novel squaraine dyes and their intermediates.
Tatarets AL, et al.
Dyes and Pigments, 64(2), 125-134 (2005)
Eileen Tan et al.
International journal of dermatology, 41(11), 748-753 (2002-11-28)
Alopecia areata is believed to be an autoimmune condition with a worldwide occurrence. It usually presents as patchy, nonscarring hair loss. There is a paucity of clinical data in Asians. To study the epidemiology, clinical aspects, associations, and treatment of
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