341738
磺酰罗丹明 B，酸式
Dye content 95 %
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关于此项目
经验公式（希尔记法）:
C27H30N2O7S2
化学文摘社编号:
分子量:
558.67
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
220-025-2
MDL number:
InChI key
IOOMXAQUNPWDLL-UHFFFAOYSA-N
InChI
1S/C27H30N2O7S2/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35)
SMILES string
CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S(O)(=O)=O)=[N+](/CC)CC)c1
form
solid
composition
Dye content, 95%
mp
>300 °C (lit.)
λmax
558 nm
Quality Level
General description
磺酰罗丹明 B (SRB) 是一种荧光蛋白染料。 据报告，染料在温和的碱性条件下与三氯乙酸固定细胞的氨基酸残基结合，并在温和的酸性条件下将其自身提取到溶液中。
Application
SRB 对其对活细胞反应性的 pH 敏感性使其可用于药物诱导的细胞毒性和细胞增殖。SRB 实验用于监测活细胞的酶活性。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The sulforhodamine B (SRB) assay was developed by Skehan and colleagues to measure drug-induced cytotoxicity and cell proliferation for large-scale drug-screening applications. Its principle is based on the ability of the protein dye sulforhodamine B to bind electrostatically and pH
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The binding of the laser dyes rhodamine B (RhB) and sulforhodamine B (kiton red S or KRS) to a cucurbit[7]uril (CB[7]) host has been investigated using density functional theory. Both guests (RhB and KRS) contain two N,N-diethylamino groups on a
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Fissistigma cavaleriei (Levl) Rehd (Annonaceae) is used as a folklore medicine for treatment of inflammation, arthritis, and tuberculosis by Miao people in China. In the present study, the antiangiogenic activity of F. cavaleriei was investigated. The chorioallantoic membrane of the
Xinyuan Chen et al.
Journal of controlled release : official journal of the Controlled Release Society, 159(1), 43-51 (2012-01-21)
Full-surface laser ablation has been shown to efficiently disrupt stratum corneum and facilitate transcutaneous drug delivery, but it is frequently associated with skin damage that hampers its clinic use. We show here that a safer ablative fractional laser (AFL) can
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