Quality Level
assay
97%
form
liquid
refractive index
n20/D 1.5754 (lit.)
bp
107-108 °C/6 mmHg (lit.)
density
1.561 g/mL at 25 °C (lit.)
functional group
acyl chloride, chloro
SMILES string
ClC(=O)c1c(Cl)cc(Cl)cc1Cl
InChI
1S/C7H2Cl4O/c8-3-1-4(9)6(7(11)12)5(10)2-3/h1-2H
InChI key
OZGSEIVTQLXWRO-UHFFFAOYSA-N
Application
2,4,6-三氯苯甲酰氯可用于制备：
- γ-内酯和 δ-内酯
- 两亲性透明质酸合成所需的脂肪族芳香酸酐
- 合成当归酯所需的混合酸酐
- spongistatin 1 和 spongistatin 2 合成
- 高产率的大环内酯。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Fieser, M.
Reagents for Organic Synthesis, 16, 353-353 (1992)
Machiko Ono et al.
Chemical & pharmaceutical bulletin, 61(4), 464-470 (2013-04-03)
Alkaline hydrolysis of 4-hydroxy- or/and 5-hydroxy-(2E)-alkenoate followed by acid treatment gave the corresponding (2E)-alkenoic acids which were subjected to lactone formation reaction without further purification. The crude acids were treated with 2,4,6-trichlorobenzoyl chloride in pyridine to afford γ-lactone or δ-lactone
Improved preparation of angelate esters.
Hartmann B, et al.
Tetrahedron Letters, 32(38), 5077-5080 (1991)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 345504-5G | 04061826760703 |