361275
3′-脱氧-3′-氟胸苷
97%
别名:
3′-Fluoro-2′,3′-dideoxythymidine, 3′-Fluorodeoxythymidine
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关于此项目
经验公式（希尔记法）:
C10H13FN2O4
化学文摘社编号:
分子量:
244.22
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
InChI
1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1
SMILES string
CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O
InChI key
UXCAQJAQSWSNPQ-XLPZGREQSA-N
assay
97%
form
solid
mp
176-178 °C (lit.)
storage temp.
2-8°C
Quality Level
Gene Information
human ... TK2(7084)
Application
具有应用前景的抗病毒试剂，活性类似于其他 3′-脱氧-3′-取代胸苷。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(9), 1630-1636 (2013-08-03)
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PloS one, 8(1), e53081-e53081 (2013-01-12)
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P Herdewijn et al.
Journal of medicinal chemistry, 30(8), 1270-1278 (1987-08-01)
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Rapid multi-tracer PET aims to image two or more tracers in a single scan, simultaneously characterizing multiple aspects of physiology and function without the need for repeat imaging visits. Using dynamic imaging with staggered injections, constraints on the kinetic behavior
Sébastien Thureau et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(9), 1543-1550 (2013-08-07)
As the preparation phase of a multicenter clinical trial using (18)F-fluoro-2-deoxy-d-glucose ((18)F-FDG), (18)F-fluoromisonidazole ((18)F-FMISO), and 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) in non-small cell lung cancer (NSCLC) patients, we investigated whether 18 nuclear medicine centers would score tracer uptake intensity similarly and define hypoxic
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