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361275

3′-脱氧-3′-氟胸苷

Name: 3′-脱氧-3′-氟胸苷
Brand: ALDRICH

97%

别名:

3′-Fluoro-2′,3′-dideoxythymidine, 3′-Fluorodeoxythymidine

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₃FN₂O₄

化学文摘社编号:

25526-93-6

分子量:

244.22

NACRES:

NA.22

PubChem Substance ID:

24862180

UNSPSC Code:

41106305

MDL number:

MFCD00056058

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属性

Quality Level

100

assay

97%

form

solid

mp

176-178 °C (lit.)

storage temp.

2-8°C

SMILES string

CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1

InChI key

UXCAQJAQSWSNPQ-XLPZGREQSA-N

Gene Information

human ... TK2(7084)

说明

Application

具有应用前景的抗病毒试剂，活性类似于其他 3′-脱氧-3′-取代胸苷。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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A series of 2',3'-unsaturated and 3'-substituted 2',3'-dideoxynucleoside analogues of purines and pyrimidines have been synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV). The 2',3'-unsaturated analogues of 2',3'-dideoxycytidine (ddeCyd) and 2',3'-dideoxythymidine (ddeThd), 3'-azido-2',3'-dideoxythymidine (AzddThd), 3'-fluoro-2',3'-dideoxythymidine, 2',3'-dideoxycytidine (ddCyd)

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J M Y Willaime et al.

Physics in medicine and biology, 58(2), 187-203 (2012-12-22)

Intra-tumour heterogeneity is a characteristic shared by all cancers. We explored the use of texture variables derived from images of [(18)F]fluorothymidine-positron emission tomography (FLT-PET), thus notionally assessing the heterogeneity of proliferation in individual tumours. Our aims were to study the

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货号	GTIN
361275-25MG	04061833279649