363308
喹诺酮 124
99%
别名:
7-Amino-4-methyl-2-hydroxyquinoline, 7-氨基-4-甲基-2-喹啉酮
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关于此项目
经验公式（希尔记法）:
C10H10N2O
化学文摘社编号:
分子量:
174.20
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
243-363-2
MDL number:
InChI key
MJXYFLJHTUSJGU-UHFFFAOYSA-N
InChI
1S/C10H10N2O/c1-6-4-10(13)12-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3,(H,12,13)
SMILES string
CC1=CC(=O)Nc2cc(N)ccc12
assay
99%
form
solid
mp
278-280 °C (lit.)
λmax
350 nm
General description
Carbostyril 124 (CS124) is a chromophore that can be used as a laser dye for sensitization and optical detection. It acts as an antenna molecule that facilitates the light absorption and enhances fluorescence efficiency.
Application
CS124 can be used in the synthesis of luminescent terbium chelates (LTCs) to develop fluoroimmunoassay for the detection of carcinoembryonic antigen. It can also be used in the development of borane lasers.
Suitable as a laser dye
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Subnanosecond light pulses from GaAs injection lasers.
Lee T and Roldan R
IEEE Journal of Quantum Electronics, 5(11), 551-552 (1969)
Modest effectiveness of carbostyril 124 as a sensitising chromophore in europium and terbium amide complexes based on 1, 4, 7, 10-tetraazacyclododecane.
Parker D and Williams JAG
J. Chem. Soc. Perkin Trans. II, 1581-1586 (1996)
G Kokotos et al.
Biological chemistry Hoppe-Seyler, 371(9), 835-840 (1990-09-01)
Sensitive and convenient fluorometric assays for the determination of chymotrypsin have been developed by using the substrates Glt-Leu-Phe-NH-Meq, Glt-Phe-NH-FMeq and Glt-Leu-Phe-NH-FMeq, which have been synthesized utilizing the mixed anhydride method. The amidolytic activity of chymotrypsin was measured by the release
A novel homogeneous time-resolved fluoroimmunoassay for carcinoembryonic antigen based on water-soluble quantum dots
Chen Z, et al.
Journal of Fluorescence, 23(4), 649-657 (2013)
M Li et al.
Bioconjugate chemistry, 8(2), 127-132 (1997-03-01)
An isothiocyanate form of a lanthanide chelate which is highly luminescent when bound to terbium or europium has been synthesized. The chelate consists of diethylenetriaminepentaacetic acid (DTPA) covalently joined to a chromophore, 7-amino-4-methyl-2(1H)-quinolinone (cs124), and to L-p-aminophenylalanine, in which the
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