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关于此项目
线性分子式:
HOC6H3(NO2)CH2OH
化学文摘社编号:
分子量:
169.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
产品名称
5-羟基-2-硝基苯甲醇, 97%
InChI
1S/C7H7NO4/c9-4-5-3-6(10)1-2-7(5)8(11)12/h1-3,9-10H,4H2
SMILES string
OCc1cc(O)ccc1[N+]([O-])=O
InChI key
ODWVFIWBWJXDMT-UHFFFAOYSA-N
assay
97%
mp
111-115 °C (lit.)
functional group
hydroxyl
nitro
Quality Level
Application
5-Hydroxy-2-nitrobenzyl alcohol may be used in the synthesis of 5-(2′-(dimethylamino)ethoxy)-2-nitrobenzyl alcohol. It may be used as difunctional photo-responsive initiator in the synthesis of thermo-responsive and photo-cleavable amphiphilic block copolymers containing photodegradable linkers as junction points between hydrophilic and hydrophobic chains.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Ren-Shen Lee et al.
Carbohydrate polymers, 117, 201-210 (2014-12-17)
In this study, we synthesized photocleavable amphiphilic block copolymers containing photodegradable linkers, 5-hydroxy-2-nitrobenzyl alcohol, as junction points between hydrophilic dextran (or maltodextrin) and hydrophobic poly(4-substituted-ɛ-caprolactone) chains, by using a combination of ring-opening polymerization and nucleophilic substitution reactions. When the polymer
Thermo-and light-regulated fluorescence resonance energy transfer processes within dually responsive microgels.
Yin J, et al.
Polym. Chem., 2(2), 363-371 (2011)
Synthesis and Characterization of Thermo-responsive and Photo-cleavable Block Copolymers as Nanocarriers.
Lee R-S, et al.
Royal Society of Chemistry Advances (2014)
Paulino Alonso-Cristobal et al.
ACS applied materials & interfaces, 7(27), 14992-14999 (2015-06-23)
Herein, we present a phototriggered drug delivery system based on light responsive nanoparticles, which is able to release doxorubicin upon NIR light illumination. The proposed system is based on upconversion fluorescence nanoparticles of β-NaYF4:Yb,Tm@SiO2-PEG with a mean diameter of 52±2.5
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