Quality Level
assay
98%
bp
86-90 °C/14 mmHg (lit.)
mp
40-42 °C (lit.)
functional group
chloro, fluoro, isocyanate
SMILES string
FC(F)(F)c1cc(ccc1Cl)N=C=O
InChI
1S/C8H3ClF3NO/c9-7-2-1-5(13-4-14)3-6(7)8(10,11)12/h1-3H
InChI key
NBJZEUQTGLSUOB-UHFFFAOYSA-N
General description
4-氯-3-（三氟甲基）苯基异氰酸酯是合成 5-甲基-3-芳基-2-硫代恶唑烷-4-酮的有效方法。
Application
4-氯-3-（三氟甲基）苯基异氰酸酯可用于合成：
- N-(5′--脱氧-3′-- O - 叔 -丁基二甲基硅基-β--D-胸苷-5′-基）- N′-（4-氯-3-三氟甲基苯基）-硫脲
- 1,3-双（4-氯-α）, α, α——三氟- m -甲苯基）脲 ]
- 反式 -1-（4-氯-3-三氟甲基-苯基）-3-（4-羟基-环己基）-脲
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
210.2 °F - closed cup
flash_point_c
99 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Hiromi I Wettersten et al.
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p21 is a member of the cyclin kinase inhibitor family of proteins and plays pivotal roles in cellular proliferation as well as in the regulation of apoptosis, and thus has diverse functions in diseases as varied as cancer and atherosclerosis.
Sung Hee Hwang et al.
Bioorganic & medicinal chemistry letters, 23(13), 3732-3737 (2013-06-04)
To reduce the pro-angiogenic effects of sEH inhibition, a structure-activity relationship (SAR) study was performed by incorporating structural features of the anti-angiogenic multi-kinase inhibitor sorafenib into soluble epoxide hydrolase (sEH) inhibitors. The structural modifications of this series of molecules enabled
Extraction and determination of the Mitins sulcofuron and flucofuron from environmental river water.
aM Hancock P.
Analyst, 123(8), 1669-1674 (1998)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 374881-5G | 04061836826642 |