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Merck
CN

375683

四乙烯五胺 五盐酸盐

98%

别名:

TEPA

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线性分子式:
HN(CH2CH2NHCH2CH2NH2)2·5HCl
化学文摘社编号:
分子量:
371.61
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
powder
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InChI

1S/C8H23N5.5ClH/c9-1-3-11-5-7-13-8-6-12-4-2-10;;;;;/h11-13H,1-10H2;5*1H

SMILES string

Cl.Cl.Cl.Cl.Cl.NCCNCCNCCNCCN

InChI key

VGICAQBLDJAGSJ-UHFFFAOYSA-N

assay

98%

form

powder

mp

280 °C (dec.) (lit.)

functional group

amine

Quality Level

General description

四乙撑五胺五盐酸盐 (Tetraethylenepentamine pentahydrochloride) 是一种具有五个胺基的胺盐,在各种反应中具有催化作用。
据报道四乙基五胺五氢氯化物为铜螯合剂。据研究报道,食用含五盐酸四乙烯五胺的铜缺乏饲料的大鼠,胰腺内分泌细胞再生。它是一种高亲和力的铜和锌螯合剂。

Application

使用 promega 的 flexi 兔网织红细胞裂解液试剂盒,盐酸四乙烯五胺适用于体外翻译。
四乙撑五胺五盐酸盐 (TETRAEN) 已被用作多胺催化剂用于胞嘧啶的亚硫酸氢盐反应。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

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I H Al-Abdullah et al.
Pancreas, 21(1), 63-68 (2000-07-06)
Transplantation of progenitor cells for regeneration of islet cells could prove invaluable in the treatment of diabetes mellitus. This study provides evidence that in rats maintained on a copper-deficient diet containing the copper-chelating agent tetraethylenepentamine pentahydrochloride, regeneration of single alpha
Schumacher's guide for: Bisulfite conversion of DNA for methylation fine-mapping.
Schumacher A.
Schumacher's Guide, 1, 1-6 (2009)
F430 Model Chemistry. A Reexamination of the [1, 4, 7, 10, 13-Pentaazacyclohexadecane-14, 16-dionato (2-)] nickel (II)-Induced Formation of Methane from Methyl Coenzyme-M.
Zhang Z, et al.
Inorganic Chemistry, 35(16), 4649-4655 (1966)
Yarui Diao et al.
The Journal of biological chemistry, 289(1), 529-539 (2013-11-20)
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma found in children and young adults. It is characterized by the expression of a number of skeletal muscle-specific proteins, including MyoD and muscle α-actin. However, unlike normal myoblasts, RMS cells differentiate
Cami K Bruns et al.
The EMBO journal, 26(3), 855-866 (2007-01-27)
Over 110 structurally diverse missense mutations in the superoxide dismutase (SOD1) gene have been linked to the pathogenesis of familial amyotrophic lateral sclerosis (FALS), yet the mechanism by which these lead to cytotoxicity still remains unknown. We have synthesized wild-type

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