Quality Level
assay
95%
refractive index
n20/D 1.444 (lit.)
bp
104-105 °C (lit.)
density
0.878 g/mL at 25 °C (lit.)
SMILES string
CC1=NCCC1
InChI
1S/C5H9N/c1-5-3-2-4-6-5/h2-4H2,1H3
InChI key
CTSZPNIMMLSKDV-UHFFFAOYSA-N
General description
2-甲基-1-吡咯啉，单环亚胺， 是一种吡咯啉衍生物。它是一种五元杂环化合物，具有多种生物学和药理学应用。它是在固定于玻璃碳电极表面上的Rh（I）络合物（含 N，N-供体配体和 N,P-供体配体）催化4-戊炔-1-胺的分子内氢化反应过程中形成的。 它可与2-氧丙醛反应生成乙酰基-1-吡咯啉（AP）。
Application
在分别从 链霉菌 GF3587和GF3546菌株中分离得到的全细胞催化剂存在的条件下，2-甲基-1-吡咯啉（2-MPN）可用于（R）-和（S）-2-甲基吡咯啉的对映体酶促合成。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
51.8 °F - closed cup
flash_point_c
11 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
María Rodríguez-Mata et al.
Chembiochem : a European journal of chemical biology, 14(11), 1372-1379 (2013-07-03)
NADPH-dependent oxidoreductase Q1EQE0 from Streptomyces kanamyceticus catalyzes the asymmetric reduction of the prochiral monocyclic imine 2-methyl-1-pyrroline to the chiral amine (R)-2-methylpyrrolidine with >99% ee, and is thus of interest as a potential biocatalyst for the production of optically active amines.
M Bertoldi et al.
The Biochemical journal, 342 Pt 3, 509-512 (1999-09-08)
Ornithine decarboxylase (ODC) from Lactobacillus 30a catalyses the cleavage of alpha-methylornithine into ammonia and 2-methyl-1-pyrroline; glutamate decarboxylase (GAD) from Escherichia coli catalyses the cleavage of alpha-methylglutamate into ammonia and laevulinic acid. In our analyses, 2-methyl-1-pyrroline and laevulinic acid were identified
2-Oxopropanal, hydroxy-2-propanone, and 1-pyrroline important intermediates in the generation of the roast-smelling food flavor compounds 2-acetyl-1-pyrroline and 2-acetyltetrahydropyridine.
Hofmann T and Schieberle P.
Journal of Agricultural and Food Chemistry, 46(6), 2270-2277 (1998)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 381055-25ML | 04061838126955 |
| 381055-5ML | 04061838126962 |