质量水平
方案
97%
反应适用性
core: gadolinium
reagent type: catalyst
mp
129 °C (dec.) (lit.)
SMILES字符串
[Gd+3].[H]O[H].OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O
InChI
1S/C14H23N3O10.Gd.H2O/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;1H2/q;+3;/p-3
InChI key
JBUMALASVLVYKI-UHFFFAOYSA-K
应用
核磁共振成像中所广泛使用的金属离子络合物,用于诊断脑肿瘤、中枢神经系统疾病、肝肿瘤、垂体腺瘤,多发性硬化症和血脑屏障损害。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Udi Vazana et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(29), 7727-7739 (2016-07-23)
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed complications. However, the mechanisms underlying
Hideki Ichikawa et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 88, 109-113 (2014-01-28)
As a nanoparticulate device for controlled delivery of Gd in NCT, the authors have developed gadolinium-loaded chitosan nanoparticles (Gd-nanoCPs). In the present study, influence of micrometric properties such as particle size, particle-surface charge and Gd content of Gd-nanoCPs on tumor-killing
E J Russell et al.
Radiology, 165(3), 609-617 (1987-12-01)
Sixteen patients with suspected cerebral metastases were studied with magnetic resonance (MR) imaging before and after the intravenous administration of 0.1 mmol/kg of gadolinium diethylenetriaminepenta-acetic acid. The images were interpreted blindly by two neuroradiologists; all clinical, radiologic (computed tomographic and
Zhengdao Xu et al.
Magma (New York, N.Y.), 34(2), 229-239 (2020-07-15)
To explore the benefits of using a single injection of contrast agent at a 1.5 T system to perform both contrast-enhanced MR angiography (MRA) and 3D-T2-STIR MR neurography (MRN) to assess of brachial plexopathy. In this prospective study, 27 patients with
Tooru Andoh et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 164, 109270-109270 (2020-08-21)
Neutron capture therapy using 157Gd (Gd-NCT) is currently under development as a cancer radiotherapy. Melanoma cells were treated with gadolinium-loaded chitosan nanoparticles (Gd-nanoCPs) for Gd-NCT. Smaller Gd-nanoCPs had higher Gd content and better cellular association of Gd and thereby made
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持