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Merck
CN

38534

Sigma-Aldrich

聚乳酸

Mw ~60,000

别名:

聚(2-羟基丙酸)

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化学文摘社编号:
MDL编号:
UNSPSC代码:
12162002
NACRES:
NA.23
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表单

solid

质量水平

保质期

limited shelf life, expiry date on the label

分子量

Mn ~30,000
Mw ~60,000

SMILES字符串

[O-]C(=O)C(O)C.[H+]

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

InChI key

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

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一般描述

聚乳酸(PLA)是一种可生物降解的聚酯 由乳酸单体通过开环聚合合成。 由于其优异的热力学、机械和阻隔性能,它被 广泛应用于组织工程,药物输送和骨科 装置。

应用

聚乳酸可以通过静电纺丝法制备成管状支架。这些支架适用于血管组织工程。

它可通过静电纺丝和涂布法制备成聚乳酸/聚乙烯醇创伤敷料膜。 PLA涂层提高了纳米纤维的机械强度,并作为保护层控制药物向伤口部位的释放。

它还可用于合成独立的,柔性的,超薄PLA纳米薄膜,可作为骨骼肌细胞粘附、扩散和增殖的基质。

特点和优势

  • 生物相容性
  • 低毒性
  • 低成本
  • 更好封装性能

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Huan Zhou et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2302-2310 (2013-03-19)
Fibrous bionanocomposites consisting of amorphous magnesium phosphate (AMP) nanospheres and polylactic acid (PLA) were fabricated by electrospinning. There are two important signatures of this paper. First, AMP, as an alternative to well-known calcium phosphate (CaP) materials, is added to PLA
Tong Chen et al.
Carbohydrate polymers, 92(2), 1124-1132 (2013-02-13)
Core-shell structured multifunctional nanocarriers (NCs) of ZnO quantum dots-conjugated gold nanoparticles (Au NPs) as core and amphiphilic hyperbranched block copolymer as shell were synthesized for targeted anticancer drug delivery. The amphiphilic hyperbranched block copolymer contained poly(l-lactide) (PLA) inner arm and
Paul S Rosen et al.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 34(1), 34-38 (2013-04-05)
This retrospective case series reports on the use of a polylactic acid barrier that was left exposed in the process of socket preparation for the placement of dental implants. A retrospective chart review found 43 patients with 48 extraction sockets
R M Felfel et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1914-1924 (2013-03-19)
Fibre reinforced composites have recently received much attention as potential bone fracture fixation applications. Bioresorbable composites based on poly lactic acid (PLA) and phosphate based glass fibre were investigated according to ion release, degradation, biocompatibility and mechanical retention profiles. The
Dah Hee Kim et al.
Carbohydrate polymers, 92(2), 1006-1011 (2013-02-13)
The purpose of this study is to evaluate the rheological and thermal properties of poly(l-lactic acid) (PLA) composites incorporated with microcrystalline cellulose (MCC) and lignin. The MCC/lignin/PLA composites were fabricated through direct melt compounding. In particular, the effect regarding the

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Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

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