38827
4,4′-二甲氧基三苯甲基氯
≥97.0% (HPLC)
别名:
4,4′-二甲氧基氯化三苯甲烷, DMT, DMT-Cl, 氯-4,4′-二甲氧基三苯基甲烷
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关于此项目
经验公式（希尔记法）:
C21H19ClO2
化学文摘社编号:
分子量:
338.83
Beilstein:
2471942
EC 号:
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥97.0% (HPLC)
mp
123-125 °C
官能团
chloro
phenyl
SMILES字符串
COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
InChI
1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
InChI key
JBWYRBLDOOOJEU-UHFFFAOYSA-N
基因信息
human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
rat ... Htr1a(24473), Htr2a(29595)
应用
4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
- For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
- For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.
其他说明
有用的保护基团试剂；移除
警示用语：
Danger
危险分类
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
8B - Non-combustible corrosive hazardous materials
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
M.D. Matteucci et al.
Tetrahedron Letters, 81, 3243-3243 (1980)
2′-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine
Seela F and Ming X
Organic & Biomolecular Chemistry, 6(8), 1450-1461 (2008)
V. Amarnath et al.
Chemical Reviews, 77, 183-183 (1977)
Yuzhe Du et al.
Molecular pharmacology, 88(2), 273-280 (2015-05-15)
Voltage-gated sodium channels are the primary target of pyrethroid insecticides. Although it is well known that specific mutations in insect sodium channels confer knockdown resistance (kdr) to pyrethroids, the atomic mechanisms of pyrethroid-sodium channel interactions are not clearly understood. Previously
Thomas F Scott et al.
Clinical neurology and neurosurgery, 127, 86-92 (2014-12-03)
To describe a "new natural history" of multiple sclerosis (MS), characterizing three patterns of progression in Relapsing MS (RMS) patients during the "treatment era," using newly developed definitions. By utilizing our simple model we intend to predict which patients are
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