398020
1,2-乙二硫醇
technical grade, ≥90%
别名:
1,2-二巯基乙烷, 二硫代乙二醇, 二硫甘醇
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关于此项目
线性分子式:
HSCH2CH2SH
化学文摘社编号:
分子量:
94.20
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-752-3
Beilstein/REAXYS Number:
505946
MDL number:
产品名称
1,2-乙二硫醇, technical grade, ≥90%
InChI key
VYMPLPIFKRHAAC-UHFFFAOYSA-N
InChI
1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2
SMILES string
SCCS
grade
technical grade
vapor density
>1 (vs air)
vapor pressure
4.8 mmHg ( 20 °C)
assay
≥90%
form
liquid
refractive index
n20/D 1.558 (lit.)
bp
144-146 °C (lit.)
mp
−41 °C (lit.)
density
1.123 g/mL at 25 °C (lit.)
functional group
thiol
Quality Level
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Application
1,2-Ethanedithiol may be used in the following studies:
- Synthesis of membrane-permeant, fluorogenic biarsenicals.
- Development of microarrays of protein interaction and quantifying the domain-peptide interactions in high throughput using fluorescently labeled synthetic peptides.
- As insolubilizing agent in a study to evaluate the structural, optical, and electrical properties of high-quality films of PbSe nanocrystals fabricated by a layer-by-layer (LbL) dip-coating method.
- Quantitation of the extent of protein phosphorylation using a phosphoprotein isotope-coded affinity tag (PhIAT).
General description
1,2-Ethanedithiol (1,2-Dimercaptoethane, Dithioglycol, Ethylene mercaptan) is an organo sulfur compound. It affords monomeric, dimeric and polymeric complexes on reaction with Pt(PPh3)4, Pd(PPh3)4 and Ni(PPh3)4. It has been synthesized by refluxing 1,2-dichloroethane with thiourea in ethanol.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
111.2 °F - closed cup
flash_point_c
44 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
The vibrational assignment, rotational isomerism and force constants of 1, 2-ethanedithiol.
Hayashi M, et al.
Bulletin of the Chemical Society of Japan, 38(10), 1734-1740 (1965)
Synthesis and reactions of new complexes of nickel, palladium, and platinum with 1, 2-ethanedithiol, 2-(methylthio) ethanethiol, and 2-(methylthio) ethane disulfide.
Rauchfuss TB and Roundhill DM.
Journal of the American Chemical Society, 97(12), 3386-3392 (1975)
M B Goshe et al.
Analytical chemistry, 73(11), 2578-2586 (2001-06-14)
A method has been developed that utilizes phosphoprotein isotope-coded affinity tags (PhIAT) that combines stable isotope and biotin labeling to enrich and quantitatively measure differences in the O-phosphorylation states of proteins. The PhIAT labeling approach involves hydroxide ion-mediated beta-elimination of
Philip Domenico et al.
Peptides, 25(12), 2047-2053 (2004-12-02)
Staphylococci are a major cause of infections associated with indwelling medical devices. Biofilm formation on these devices adds to the antibiotic resistance seen among clinical isolates. RNAIII-inhibiting peptide (RIP) is a heptapeptide that inhibits staphylococcal pathogenesis, including biofilm formation, by
Majed Halwani et al.
International journal of pharmaceutics, 373(1-2), 141-146 (2009-05-12)
Recurrent pulmonary infection and inflammation are major risk factors for high morbidity and mortality in patients with cystic fibrosis (CF). As such, frequent antibiotic use and drug resistant bacterial strains are main concerns in individuals with CF. Bacterial virulence and
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