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402516

1H-吡唑-1-甲脒 盐酸盐

99%

别名:

1H-吡唑-1-甲脒盐酸盐, 吡唑-1-氨基亚胺 盐酸盐

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关于此项目

经验公式（希尔记法）:
C4H6N4 · HCl
化学文摘社编号:
4023-02-3
分子量:
146.58
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24865095
EC Number:
429-520-1
Beilstein/REAXYS Number:
5448758
MDL number:
MFCD00210087
Assay:
99%
Form:
powder
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Quality Level

200

assay

99%

form

powder

mp

167-170 °C (lit.)

functional group

amine

SMILES string

Cl[H].NC(=N)n1cccn1

InChI

1S/C4H6N4.ClH/c5-4(6)8-3-1-2-7-8;/h1-3H,(H3,5,6);1H

InChI key

RBZRMBCLZMEYEH-UHFFFAOYSA-N

General description

1H-吡唑-1-甲酰脒盐酸盐为吡唑衍生物，为杂环化合物。在药物合成研究中应用广泛。吡唑环构成了各种非甾体抗炎药 (NSAIDs) 和抗高血压药物的主要核心。

Application

1H-吡唑-1-甲脒盐酸盐可用于以下研究：
  • 胍基中空纤维膜的制备。
  • 胺类的鸟苷酸化和肽合成。
  • 双胍胆固醇衍生物的合成。

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCV6621
MKCR1597
MKCR6111
MKCN8617
MKAA1237V

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J P Vigneron et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(18), 9682-9686 (1996-09-03)
Two cationic lipids, bis-guanidinium-spermidine-cholesterol (BGSC) and bis-guanidinium-trencholesterol (BGTC)-cholesterol derivatives bearing two guanidinium groups-have been synthesized and tested as artificial vectors for gene transfer. They combine the membrane compatible features of the cholesterol subunit and the favorable structural and high pKa
Hironori Izawa et al.
Biomolecules, 9(7) (2019-07-10)
In order to synthesize a promising material for developing a novel peptide/protein delivery system, guanidinylation of chitooligosaccharides with 1-amidinopyrazole hydrochloride was investigated herein. The production of guanidinylated chitooligosaccharides was demonstrated by infrared spectroscopy (IR), nuclear magnetic resonance (NMR), and elemental
Xiao Zhang et al.
ACS applied materials & interfaces, 12(14), 16088-16096 (2020-03-17)
Supramolecular hydrogels have great potential as biomaterials for tissue engineering applications or vehicles for delivering therapeutic agents. Herein, a self-healing and pro-osteogenic hydrogel system is developed based on the self-assembly of laponite nanosheets and guanidinylated chitosan, where laponite works as
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全球贸易项目编号

货号GTIN
402516-10G04061832993638
402516-50G04061831985900