40407
1,7-二甲基尿酸
≥97.0% (HPLC)
别名:
1,7-二甲基-2,6,8-三羟基嘌呤
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关于此项目
经验公式（希尔记法）:
C7H8N4O3
化学文摘社编号:
分子量:
196.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
251-706-2
Beilstein/REAXYS Number:
219682
MDL number:
Assay:
≥97.0% (HPLC)
Quality Level
assay
≥97.0% (HPLC)
SMILES string
CN1C(=O)NC2=C(N(C)C(=O)N2)C1=O
InChI
1S/C7H8N4O3/c1-10-3-4(8-6(10)13)9-7(14)11(2)5(3)12/h1-2H3,(H,8,13)(H,9,14)
InChI key
NOFNCLGCUJJPKU-UHFFFAOYSA-N
General description
1,7-Dimethyluric acid is an important metabolite of caffeine. Electrochemical oxidation of 1,7-dimethyluric acid was studied over a wide pH range of 2.2-10.3 at solid electrodes.
Application
1,7-Dimethyluric acid is the suitable reagent used for the simultaneous determination of plasma levels of theophylline and its metabolites without interference from caffeine or caffeine metabolites by HPLC.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Emma Gracia-Lor et al.
The Science of the total environment, 747, 141331-141331 (2020-08-18)
Smoking cigarettes and drinking coffee are common habits in today's society. However, it is not easy to get up-to-date information on smoking prevalence and caffeine consumption as it is usually obtained from population surveys. To overcome this limitation and complement
J Kizu et al.
Biomedical chromatography : BMC, 13(1), 15-23 (1999-04-07)
A high performance liquid chromatography (HPLC) method has been developed for the simultaneous determination of plasma levels of theophylline and its metabolites without interference from caffeine or caffeine metabolites. The method is simple and of practical use because it is
K L Rost et al.
Clinical pharmacology and therapeutics, 55(4), 402-411 (1994-04-01)
Omeprazole has previously been shown to induce hepatic cytochrome P4501A2 activity, as evidenced by an accelerated N-3-demethylation in the 13C-[N-3-methyl]-caffeine breath test. In this study we investigated whether the inducing potency of omeprazole can be quantified by the determination of
Electrochemical and peroxidase catalysed oxidation of 1, 7-dimethyluric acid and effect of methyl groups on the oxidation mechanism.
Goyal RN, et al.
J. Chem. Soc. Perkin Trans. II, 6, 1153-1159 (1996)
E Asprodini et al.
The Journal of pharmacology and experimental therapeutics, 368(2), 262-271 (2018-12-29)
The purpose of the study was to determine whether the in vivo activities of drug-metabolizing enzymes CYP1A2 and CYP2A6, xanthine oxidase (XO), and N-acetyltransferase-2 (NAT2) vary across the menstrual cycle. Forty-two healthy women were studied at early follicular phase (EFP:
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 40407-250MG | 04061833279915 |
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