四羟甲基氯化磷溶液

Name: 四羟甲基氯化磷 溶液
Brand: ALDRICH

80% in H2O, liquid

别名:

THPC溶液

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关于此项目

线性分子式:

(HOCH₂)₄PCl

化学文摘社编号:

124-64-1

分子量:

190.56

NACRES:

NA.22

PubChem Substance ID:

24865276

UNSPSC Code:

12352101

MDL number:

MFCD00031687

Beilstein/REAXYS Number:

3631669

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产品名称

四羟甲基氯化磷溶液, 80% in H₂O

InChI

1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1

SMILES string

[Cl-].OC[P+](CO)(CO)CO

InChI key

AKXUUJCMWZFYMV-UHFFFAOYSA-M

form

liquid

concentration

80% in H₂O

refractive index

n20/D 1.512

density

1.341 g/mL at 25 °C

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Application

四羟甲基氯化磷溶液（80%,溶剂为H₂O）已被用作从四氯金酸三水合物(HAuCl₄.3H₂O)合成金纳米颗粒（AuNP）的还原剂和稳定配体。它是一种四官能团胺反应性水性交联剂，可调节蛋白质水凝胶的性质以用于3D细胞封装应用。

pictograms

GHS06,GHS08,GHS05,GHS09

signalword

Danger

hcodes

H290,H301 + H311,H314,H317,H360FD,H410

pcodes

P201 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

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Facile preparation of water-soluble fluorescent gold nanoclusters for cellular imaging applications.

Shang L, et al.

Nanoscale, 3(5), 2009-2014 (2011)

Beyond gold: rediscovering tetrakis-(hydroxymethyl)-phosphonium chloride (THPC) as an effective agent for the synthesis of ultra-small noble metal nanoparticles and Pt-containing nanoalloys

Hueso J L, et al.

Royal Society of Chemistry Advances, 3(26), 10427-10433 (2013)

Clinical feasibility of monitoring m-THPC mediated photodynamic therapy by means of fluorescence differential path-length spectroscopy.

Baris Karakullukcu et al.

Journal of biophotonics, 4(10), 740-751 (2011-08-24)

The objective quantitative monitoring of light, oxygen, and photosensitizer is challenging in clinical photodynamic therapy settings. We have previously developed fluorescence differential path-length spectroscopy (FDPS), a technique that utilizes reflectance spectroscopy to monitor microvascular oxygen saturation, blood volume fraction, and

Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels.

Cindy Chung et al.

Biomacromolecules, 13(12), 3912-3916 (2012-11-16)

Native tissues provide cells with complex, three-dimensional (3D) environments comprised of hydrated networks of extracellular matrix proteins and sugars. By mimicking the dimensionality of native tissue while deconstructing the effects of environmental parameters, protein-based hydrogels serve as attractive, in vitro

Uptake and phototoxicity of meso-tetrahydroxyphenyl chlorine are highly variable in human biliary tract cancer cell lines and correlate with markers of differentiation and proliferation.

Tobias Kiesslich et al.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9(5), 734-743 (2010-04-02)

Photodynamic therapy (PDT) using Photofrin and, recently, Foscan has gained broad acceptance for palliative treatment of non-resectable cholangiocarcinoma (CC). No information, however, is available whether the phenotype of CC tumour cells has an effect on the efficiency of the treatment.

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四羟甲基氯化磷溶液

80% in H2O, liquid