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Merck
CN

408719

支化聚乙烯亚胺

average Mw ~800 by LS, average Mn ~600 by GPC

别名:

PEI, 支化乙二胺

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关于此项目

线性分子式:
H(NHCH2CH2)nNH2
化学文摘社编号:
25987-06-8
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00084427

主要文件

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产品名称

支化聚乙烯亚胺, average Mw ~800 by LS, average Mn ~600 by GPC

SMILES string

N1CC1.NCCN

InChI

1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2

InChI key

SFLOAOINZSFFAE-UHFFFAOYSA-N

form

viscous liquid

mol wt

average Mn ~600 by GPC
average Mw ~800 by LS

refractive index

n20/D 1.5240

density

1.050 g/mL at 25 °C

Quality Level

200

相关类别

Application

支链型PEI可作为前体合成共轭多聚体，用于高效基因转染。PEI与Jeffamine聚醚的共轭化和PEI氨基的胍化可降低多聚体的细胞毒性，并保护其在血清蛋白存在下不会发生聚焦。

PEI 浸渍竹炭可用作CO2吸附剂。PEI中存在大量的氨基基团，可在酸碱作用下与CO2发生反应，增强竹炭的吸附能力。

它还可用于制备对有机药物分子具有高配位能力的交联水溶性聚合物。

Features and Benefits

  • 支链型PEI具有较好的络合 能力和缓冲能力。
  • 高离子交换 能力和对蛋白质的亲和力。
  • 显著的DNA转移效率。

General description

聚乙烯亚胺是一种亲水性聚合物，作为一种非病毒合成载体，广泛用于体内递送治疗性核酸。由于其优异的理化性质，它被应用于蛋白质的分离和纯化、二氧化碳吸收、药物载体、废水处理、生物标记等多个领域。

Physical form

支化聚合物

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

356.0 °F

flash_point_c

180 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF7584V
WXBF5953V
WXBF4895V
MKCV6718
MKCJ2767

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