410403
2-肼基-4-三氟甲基嘧啶
99%
方案
99%
mp
99-101 °C (lit.)
SMILES字符串
NNc1nccc(n1)C(F)(F)F
InChI
1S/C5H5F3N4/c6-5(7,8)3-1-2-10-4(11-3)12-9/h1-2H,9H2,(H,10,11,12)
InChI key
XQCAINVUBSAUBJ-UHFFFAOYSA-N
应用
2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used in the following studies:
- As derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum samples by liquid chromatography-electrospray ionization-tandem mass spectrometry.
- Synthesis of organohydrazide chelate complexes of rhenium and technetium, having a metal-nitrogen-nitrogen linkage.
- Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Jukkarin Srivilai et al.
Steroids, 116, 67-75 (2016-10-31)
Steroid 5α-reductase (S5αR) plays an important role in metabolizing testosterone into active androgen dihydrotestosterone (DHT) which is involved in many androgen dependent disorders, such as androgenic alopecia, benign prostatic hyperplasia and acne. The method for screening for S5αR inhibition is
Shailendra Kumar Sharma et al.
The Journal of biological chemistry, 278(46), 45661-45671 (2003-08-22)
The emergence of drug-resistant forms of Plasmodium falciparum emphasizes the need to develop new antimalarials. In this context, the fatty acid biosynthesis (FAS) pathway of the malarial parasite has recently received a lot of attention. Due to differences in the
Yan Weng et al.
Analytical biochemistry, 402(2), 121-128 (2010-04-07)
A novel method was established for simultaneous quantitation of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum samples. Endogenous T and DHT, together with the internal standards 17alpha-methyl-T and 17alpha-methyl-DHT, were extracted from tissues and then derivatized by
The synthesis and characterization of technetium and rhenium hydrazinopyrimidine chelate complexes.
Hirsch-Kuchma M, et al.
J. Chem. Soc., Dalton Trans., 18, 3185-3188 (1997)
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