412562
(S)-(-)-二氨基丙烷 二盐酸盐
99%
别名:
(S)-(-)-丙二胺 二盐酸盐, (S)-1,2-丙二胺 二盐酸盐
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关于此项目
线性分子式:
CH3CH(NH2)CH2NH2·2HCl
化学文摘社编号:
分子量:
147.05
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5740936
Assay:
99%
Quality Level
assay
99%
optical activity
[α]22/D −4°, c = 20 in H2O
mp
227-229 °C (lit.)
functional group
amine
SMILES string
Cl.Cl.C[C@H](N)CN
InChI
1S/C3H10N2.2ClH/c1-3(5)2-4;;/h3H,2,4-5H2,1H3;2*1H/t3-;;/m0../s1
InChI key
AEIAMRMQKCPGJR-QTNFYWBSSA-N
Application
(S)-(-)-1,2-Diaminopropane dihydrochloride may be used in the preparation of following chiral imidazoline derivatives, which show moderate α-adrenergic blocking activity:
- (S)-(-)-4-methyl-2-(1-naphthylmethyl)imidazoline hydrochloride
- (S)-(-)-2-benzyl-4-methylimidazoline picrate
- (S )-(-)-2-[(2,6-dichlorophenyl)imino]-4-methylimidazolidine hydrochloride
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Optically active derivatives of imidazolines: a-Adrenergic blocking properties.
Hsu FL, et al.
Journal of Medicinal Chemistry, 23(11), 1232-1235 (1980)
Stereochemical studies of adrenergic drugs. Optically active derivatives of imidazolines.
Miller DD, et al.
Journal of Medicinal Chemistry, 19(12), 1382-1384 (1976)
Lorin A Thompson et al.
Bioorganic & medicinal chemistry letters, 21(22), 6909-6915 (2011-10-07)
The synthesis, evaluation, and structure-activity relationships of a set of related constrained diaminopropane inhibitors of BACE-1 are described. The full in vivo profile of an optimized inhibitor in both normal and P-gp deficient mice is compared with data generated in
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 412562-1G | 04061832076089 |