质量水平
方案
99%
mp
152-154 °C (lit.)
官能团
ketone
SMILES字符串
CC(C)(C)C1=CC(=O)C(=CC1=O)C(C)(C)C
InChI
1S/C14H20O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8H,1-6H3
InChI key
ZZYASVWWDLJXIM-UHFFFAOYSA-N
一般描述
2,5-二叔丁基-1,4-苯醌（DTBBQ）是一种2,5-二取代醌。它是一种从海洋链霉菌Streptomyces sp. VITVSK1中分离出来的抗菌化合物。 已有研究使用高压EPR技术，评估了2,5-二叔丁基-1,4-苯醌离子对中Na+和K+的分子内和分子间迁移速率的压力依赖性。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
J K Foskett et al.
The American journal of physiology, 262(3 Pt 1), C656-C663 (1992-03-01)
Previous studies have demonstrated in single rat parotid acinar cells that the microsomal Ca(2+)-ATPase inhibitor thapsigargin mobilizes Ca2+ specifically from the inositol 1,4,5-trisphosphate (IP3)-sensitive Ca2+ store, activates plasma membrane Ca2+ permeability, and induces intracellular Ca2+ concentration ([Ca2+]i) oscillations that are
M Wictome et al.
Biochemical and biophysical research communications, 199(2), 916-921 (1994-03-15)
Trilobolide and 2,5-di(tert-butyl)-1,4-benzohydroquinone (BHQ) are potent inhibitors of the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum. Desoxytrilobolide and 2,5-di(tert-butyl)-1,4-diacetylphenol (acetyl-BHQ) have much lower potencies than their parent compounds and 2,5-di(tert-butyl)-1,4-benzoquinone (BQ) has no effect on ATPase activity. Studies using the ATPase
G Reiser et al.
Experimental cell research, 202(2), 440-449 (1992-10-01)
Continuous superfusion of rat glioma cells with medium containing bradykinin (from 0.2 nM) induced a transient hyperpolarization followed by regular hyperpolarizing oscillations of the membrane potential. Similar repetitive hyperpolarizing oscillations were caused by extracellularly applied bradykinin or muscarine or by
P Adams et al.
The Biochemical journal, 335 ( Pt 1), 131-138 (1998-09-22)
Mutational analysis of trans-membrane helices M3, M4, M5 and M7 of the Ca2+-ATPase revealed a novel phenotypic variant, M4 [Y295A (the one-letter symbols are used for amino acid residues throughout)], displaying an increased affinity for Pi and decreased affinity for
H Westerblad et al.
The Journal of physiology, 474(2), 291-301 (1994-01-15)
1. Intracellular calcium concentration ([Ca2+]i) and force were measured from isolated single mouse skeletal muscle fibres at rest and during tetani. The actions of 2,5-di(tert-butyl)-1,4-benzohydroquinone (TBQ), an inhibitor of the sarcoplasmic reticulum (SR) Ca2+ pump, were examined at a range
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