420247
(+)-冰片
97%
别名:
内型-(1R)-1,7,7-三甲基二环[2.2.1]庚-2-醇
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关于此项目
经验公式（希尔记法）:
C10H18O
化学文摘社编号:
分子量:
154.25
UNSPSC Code:
12352212
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-352-6
Beilstein/REAXYS Number:
2038056
MDL number:
产品名称
(+)-冰片, 97%
InChI key
DTGKSKDOIYIVQL-WEDXCCLWSA-N
InChI
1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1
SMILES string
[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C
assay
97%
form
solid
optical activity
[α]20/D +36°, c = 5 in ethanol
mp
206-209 °C (lit.)
functional group
hydroxyl
Quality Level
Gene Information
human ... UGT1A4(54657)
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Application
(+)-冰片在人神经母细胞瘤细胞（SH-SY5Y）中已被用于研究其对抗凋亡、抗氧化和神经保护作用。
General description
(+)-冰片是一种双环单萜，于药用植物精油中发现，常用于中药，起到镇痛和麻醉作用。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
signalword
Warning
hcodes
Hazard Classifications
Flam. Sol. 2
存储类别
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
149.0 °F - closed cup
flash_point_c
65 °C - closed cup
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Liang Zou et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(22), 3490-3493 (2013-02-05)
To explore the influence of borneol on intestinal absorption of muscone in rats. An in situ intestinal circulation perfusion experiment was used to study the changes in intestinal absorption kinetics of muscone before and after being compatible with borneol. Compared
Wan Ren-Zhong et al.
Journal of Asian natural products research, 14(6), 538-544 (2012-05-17)
The main purpose of this study was to illustrate the effect of borneol on pharmacokinetics of salvianolic acid B (SalB) in rats after oral administration of SalB with different doses of borneol. The concentrations of SalB in rat plasma were
Jianyu Su et al.
Journal of food science, 77(6), C658-C664 (2012-05-16)
The aims of this study were to optimize the preparation conditions of natural borneol/β-cyclodextrin (NB/β-CD) inclusion complex by ultrasound method, and to investigate its improvement of stability and solubility. The complex was characterized by different various spectroscopic techniques including Fourier
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