420247
(+)-冰片
97%
别名:
内型-(1R)-1,7,7-三甲基二环[2.2.1]庚-2-醇
质量水平
方案
97%
表单
solid
旋光性
[α]20/D +36°, c = 5 in ethanol
mp
206-209 °C (lit.)
官能团
hydroxyl
SMILES字符串
[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C
InChI
1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1
InChI key
DTGKSKDOIYIVQL-WEDXCCLWSA-N
基因信息
human ... UGT1A4(54657)
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一般描述
(+)-冰片是一种双环单萜,于药用植物精油中发现,常用于中药,起到镇痛和麻醉作用。
应用
(+)-冰片在人神经母细胞瘤细胞(SH-SY5Y)中已被用于研究其对抗凋亡、抗氧化和神经保护作用。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
警示用语:
Warning
危险声明
危险分类
Flam. Sol. 2
储存分类代码
4.1B - Flammable solid hazardous materials
WGK
WGK 3
闪点(°F)
149.0 °F - closed cup
闪点(°C)
65 °C - closed cup
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jianyu Su et al.
Journal of food science, 77(6), C658-C664 (2012-05-16)
The aims of this study were to optimize the preparation conditions of natural borneol/β-cyclodextrin (NB/β-CD) inclusion complex by ultrasound method, and to investigate its improvement of stability and solubility. The complex was characterized by different various spectroscopic techniques including Fourier
Liang Zou et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(22), 3490-3493 (2013-02-05)
To explore the influence of borneol on intestinal absorption of muscone in rats. An in situ intestinal circulation perfusion experiment was used to study the changes in intestinal absorption kinetics of muscone before and after being compatible with borneol. Compared
Wan Ren-Zhong et al.
Journal of Asian natural products research, 14(6), 538-544 (2012-05-17)
The main purpose of this study was to illustrate the effect of borneol on pharmacokinetics of salvianolic acid B (SalB) in rats after oral administration of SalB with different doses of borneol. The concentrations of SalB in rat plasma were
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