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线性分子式:
NH2(CH2)6NH(CH2)6NH2
化学文摘社编号:
分子量:
215.38
EC Number:
205-593-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
2323517
MDL number:
InChI key
MRNZSTMRDWRNNR-UHFFFAOYSA-N
InChI
1S/C12H29N3/c13-9-5-1-3-7-11-15-12-8-4-2-6-10-14/h15H,1-14H2
SMILES string
NCCCCCCNCCCCCCN
grade
technical grade
vapor pressure
<0.01 mmHg ( 25 °C)
concentration
40%
refractive index
n20/D 1.49 (lit.)
bp
163-165 °C/4 mmHg (lit.)
mp
33-36 °C (lit.)
density
0.85 g/mL at 20 °C (lit.), 0.931 g/mL at 25 °C
General description
Bis(hexamethylene)triamine is an aliphatic polyamine. It is a spermidine analog and has been reported to lack the enhancing effect on mitochondrial Ca(2+) accumulation but shows inhibitory effect on the Ca(2+) and Pi-induced mitochondrial permeability transition.
Application
Bis(hexamethylene)triamine is the suitable reagent used in the synthesis of xylylated dimer of polyamine and as a solvent to coat amphiphilic polymer on CdSe/ZnS quantum dots (QDs) for enhanced water solubilization.
It may be used in the following studies:
It may be used in the following studies:
- Synthesis of bis(hexamethylene) triacetamide (BHTA) by acetylation.
- As a precursors for the ZnO outgrowths on TiO2 nanofibers.
- As organic bifunctional guest molecules for {W36} polyoxotungstate host compounds to form 1D chains of directly connected {W36} cluster units.
Legal Information
DuPont 产品
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
I Rustenbeck et al.
Biochemistry and molecular biology international, 38(5), 1003-1011 (1996-04-01)
The aliphatic polyamine bis(hexamethylene)triamine, a spermidine analogue, was found to lack the enhancing effect on mitochondrial Ca(2+) accumulation which is typical for the natural polyamines, spermidine and spermine. However, like spermine and spermidine, this compound had a significant inhibitory effect
Titanium oxide nanofibers attached to zinc oxide nanobranches as a novel nano-structure for lithium ion batteries applications.
Kime HY.
Journal of Ceramic Processing Research, 11(4), 437-442 (2010)
P A Marks et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(16), 6358-6362 (1989-08-01)
N,N'-Hexamethylenebisacetamide (HMBA) induces transformed cells to differentiate, accompanied by suppression of oncogenicity. Clinical trials have shown that HMBA can cause positive therapeutic responses in some cancer patients, but clinical efficacy may be limited, in part, by dose-related toxicity. Potential improvements
Laurence Covassin et al.
Bioorganic & medicinal chemistry letters, 13(19), 3267-3271 (2003-09-03)
Dimeric norspermidine and spermidine derivatives are strong competitive inhibitors of polyamine transport. A xylyl tether was used for the dimerization of various triamines and spermine via a secondary amino group, and of putrescine via an ether or an amino group.
Development of high dispersed TiO2 paste for transparent screen-printable self-cleaning coatings on glass
Wang Y, et al.
Journal of Nanoparticle Research, 15(1), 1-6 (2013)
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