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Merck
CN

422754

3-癸炔-1-醇

97%

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线性分子式:
CH3(CH2)5C≡CCH2CH2OH
化学文摘社编号:
分子量:
154.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Form:
liquid
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产品名称

3-癸炔-1-醇, 97%

InChI

1S/C10H18O/c1-2-3-4-5-6-7-8-9-10-11/h11H,2-6,9-10H2,1H3

SMILES string

CCCCCCC#CCCO

InChI key

YGEQBZUDPQQIFI-UHFFFAOYSA-N

assay

97%

form

liquid

refractive index

n20/D 1.459 (lit.)

bp

130-131 °C/22 mmHg (lit.)

density

0.877 g/mL at 25 °C (lit.)

functional group

hydroxyl

Application

3-Decyn-1-ol may be used in the following studies:
  • As a starting material in the synthesis of 3′-deoxyribolactones.
  • As a starting material in the synthesis of (Z)-3-decen-1-ol by hydrogenation over P-2 nickel.
  • As a reagent in the synthesis of methyl 9-decynoate.

General description

3-Decyn-1-ol is primary homo-propargylic alcohol derivative. It has been reported to be formed during the isomerization of 2-decyn-1-ol in the presence of sodium salt of 1,3-diaminopropane. Its toxicity has been evaluated on the green alga, Pseudokirchneriella subcapitata in terms of EC50 (median effective concentration) and NOEC (no observed effect level) values. It undergoes semi hydrogenation in the presence of Lindlar catalyst to form cis-3-decen-1-ol.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

224.6 °F - closed cup

flash_point_c

107 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

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The rearrangement of isomeric linear decyn-1-ols by reaction with the sodium salt of 1, 3-diaminopropane.
Macaulay SR.
Canadian Journal of Chemistry, 58(23), 2567-2572 (1980)
Seiji Itoh et al.
Bioscience, biotechnology, and biochemistry, 66(7), 1591-1596 (2002-09-13)
Both the (17R)- and (17S)-isomers of volicitin, which is contained in the oral secretion of the beet armyworm and induces corn seedlings to emit a blend of volatile compounds to attract the natural enemy of the herbivore, were synthesized via
Synthesis of 3'-Deoxyribolactones using a Hydrolysis-Induced Lactonization Cascade Reaction of Epoxy Cyanohydrins.
Vugts DJ, et al.
European Journal of Organic Chemistry, 2008(8), 1336-1339 (2008)
Tonibelle N Gatbonton-Schwager et al.
Redox biology, 2, 755-763 (2014-07-11)
4-Hydroxy-2-(E)-nonenal (4-HNE) is one of the major lipid peroxidation product formed during oxidative stress. At high concentrations, 4-HNE is cytotoxic and exerts deleterious effects that are often associated with the pathology of oxidative stress-driven disease. Alternatively, at low concentrations it
Chung Yuan Chen et al.
Journal of environmental monitoring : JEM, 14(1), 181-186 (2011-11-23)
The present study evaluates the toxicity of 34 propargylic alcohols, including primary, primary homo-, secondary, and tertiary alcohols, based on their effects on phytoplankton. A closed-system algal toxicity test was applied because the closed-system technique presents more realistic concentration-response relationships

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