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Merck
CN

428426

(2-溴乙氧基)-叔丁基二甲基硅烷

99%

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线性分子式:
BrCH2CH2OSi(CH3)2C(CH3)3
化学文摘社编号:
分子量:
239.23
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
99%
Form:
liquid
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产品名称

(2-溴乙氧基)-叔丁基二甲基硅烷, 99%

InChI

1S/C8H19BrOSi/c1-8(2,3)11(4,5)10-7-6-9/h6-7H2,1-5H3

SMILES string

CC(C)(C)[Si](C)(C)OCCBr

InChI key

JBKINHFZTVLNEM-UHFFFAOYSA-N

assay

99%

form

liquid

contains

Na2CO3 as stabilizer

refractive index

n20/D 1.444 (lit.)

bp

70-75 °C/2.5 mmHg (lit.)

density

1.115 g/mL at 25 °C (lit.)

functional group

bromo

storage temp.

2-8°C

Quality Level

Application

(2-溴乙氧基)--丁基二甲基硅烷用于 4-(3-羟丙基)-4'-甲基-2,2'-联吡啶的合成。
可用作 5-哌嗪-1-基-1 H -吲哚和(1 H -吲哚-2-基)-哌嗪-1-基-甲酮的选择性 N -烷基化试剂 ,也可用于合成 2-[3-[[(3,4,5-三甲氧基苯基)硫代]-1 H -吲哚-5-氧基] 乙醇。

General description

(2-溴乙氧基)-叔丁基二甲基硅烷是一种硅烷衍生物。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

163.4 °F - closed cup

flash_point_c

73 °C - closed cup


历史批次信息供参考:

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Hansen, Joshua; et al.
Tetrahedron Letters, 47(1), 69-72 (2005)
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La Regina G, et al.
Journal of Medicinal Chemistry, 50(12), 2865-2874 (2007)
Cyril Bressy et al.
Journal of the American Chemical Society, 127(38), 13148-13149 (2005-09-22)
A norbornene-mediated palladium-catalyzed tandem alkylation/C-H functionalization sequence is described, in which an alkyl-aryl bond and a heteroaryl-aryl bond are formed in one pot. A variety of highly substituted six- and seven-membered ring annulated indoles were synthesized in good yields from
Mark Johnson et al.
Journal of medicinal chemistry, 55(12), 5826-5840 (2012-05-31)
In our effort to develop multifunctional drugs against Parkinson's disease, a structure-activity-relationship study was carried out based on our hybrid molecular template targeting D2/D3 receptors. Competitive binding with [(3)H]spiroperidol was used to evaluate affinity (K(i)) of test compounds. Functional activity

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