433829
4-肼基苯甲酸 盐酸盐
98%
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关于此项目
线性分子式:
H2NNHC6H4CO2H · HCl
化学文摘社编号:
分子量:
188.61
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
98%
mp
253 °C (dec.) (lit.)
官能团
carboxylic acid
hydrazine
储存温度
2-8°C
SMILES字符串
Cl.NNc1ccc(cc1)C(O)=O
InChI
1S/C7H8N2O2.ClH/c8-9-6-3-1-5(2-4-6)7(10)11;/h1-4,9H,8H2,(H,10,11);1H
InChI key
XHLQMKQBCHYRLC-UHFFFAOYSA-N
一般描述
4-Hydrazinobenzoic acid (p-Hydrazinobenzoic acid, HBA) has been reported as an ingredient of the cultivated mushroom Agaricus bisporus. It is carcinogenic to rodents. Mechanism of DNA damage by 4-hydrazinobenzoic acid has been studied by using 32P-labeled DNA fragments obtained from the human p53 and p16 tumor suppressor genes. It may be used for the preparation of 4-(3-(2-(tert-butoxycarbonylamino)ethyl)-5-hydroxy-1H-pyrazol-1-yl)benzoic acid.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Synthesis of 3-(2-aminoethyl)-5-hydroxy-1H-pyrazole derivatives.
Groselj U, et al.
ARKIVOC (Gainesville, FL, United States), 3, 49-65 (2012)
Yan-Juan Gu et al.
International journal of nanomedicine, 6, 2889-2898 (2011-12-02)
Single-walled carbon nanotubes (SWNTs) have been identified as an efficient drug carrier. Here a controlled drug-delivery system based on SWNTs coated with doxorubicin (DOX) through hydrazone bonds was developed, because the hydrazone bond is more sensitive to tumor microenvironments than
B M McManus et al.
Laboratory investigation; a journal of technical methods and pathology, 57(1), 78-85 (1987-07-01)
p-Hydrazinobenzoic acid (HBA), an ingredient of the cultivated mushroom Agaricus bisporus, was given in hydrochloride form at a dosage of 0.125% in drinking water for life to randomly bred Swiss mice. Previous studies had demonstrated that either synthetic or naturally
Yun-Gon Kim et al.
Chemistry & biology, 15(3), 215-223 (2008-03-22)
Glycan recognition leading to cell-cell interactions, signaling, and immune responses is mediated by various glycan-binding proteins (GBPs) showing highly diverse ligand specificities. We describe here a rapid glycan immobilization technique via 4-hydrazinobenzoic acid (HBA)-functionalized beads and its application to high-throughput
X Wang et al.
Carbohydrate research, 332(2), 191-196 (2001-07-04)
p-Hydrazinobenzenesulfonic acid was explored as an ultraviolet labeling reagent for capillary electrophoresis of mono-, di- and trisaccharides. The labeling reaction that produces p-sulfophenylhydrazines took less than 8 min, and introduced both chromphore and charged groups into the carbohydrate molecules. The
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