方案
95%
表单
liquid
折射率
n20/D 1.511 (lit.)
沸点
115 °C/0.015 mmHg (lit.)
密度
1.225 g/mL at 25 °C (lit.)
SMILES字符串
CCOC(=O)c1ccc(CCl)o1
InChI
1S/C8H9ClO3/c1-2-11-8(10)7-4-3-6(5-9)12-7/h3-4H,2,5H2,1H3
InChI key
JBACYJRMCXLIQU-UHFFFAOYSA-N
应用
Ethyl 5-(chloromethyl)-2-furancarboxylate may be employed for the synthesis of a series of novel sulfamide- and urea-based small-molecule antagonists of the protein-protein interaction IL-2/IL-2Rα. It may be employed as starting material for the synthesis of 5-hydroxymethylfuran-2-carboxylic acid.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
法规信息
新产品
此项目有
Nathan D Waal et al.
Bioorganic & medicinal chemistry letters, 15(4), 983-987 (2005-02-03)
The identification, design, and synthesis of a series of novel sulfamide- and urea-based small-molecule antagonists of the protein-protein interaction IL-2/IL-2Ralpha are described. Installation of a furan carboxylic acid fragment onto a low-micromolar sulfamide resulted in a 23-fold improvement in activity
Shintaro Hara et al.
PloS one, 7(7), e41142-e41142 (2012-08-01)
Many investigators have recognised that a significant proportion of environmental bacteria exist in a viable but non-culturable state on agar plates, and some researchers have also noticed that some of such bacteria clearly recover their growth on matrices other than
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