436917
1H-四唑-5-乙酸乙酯
97%
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关于此项目
经验公式（希尔记法）:
C5H8N4O2
化学文摘社编号:
分子量:
156.14
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
97%
mp
123-127 °C (lit.)
官能团
ester
SMILES字符串
CCOC(=O)Cc1nnn[nH]1
InChI
1S/C5H8N4O2/c1-2-11-5(10)3-4-6-8-9-7-4/h2-3H2,1H3,(H,6,7,8,9)
InChI key
NAOHMNNTUFFTBF-UHFFFAOYSA-N
一般描述
Ethyl 1H-tetrazole-5-acetate is a tetrazole derivative. Its effect on glutaminyl cyclase activity of the recombinant human glutaminyl cyclase (QC) has been reported.
应用
Ethyl 1H-tetrazole-5-acetate (Ethyl 1H-tetrazole-5-yl acetate, Hetza) may be employed as starting reagent for the synthesis of ethyl aryloxadiazolylacetates. It may be used for the preparation of homochiral 3D diamondoid metal-organic framework [Zn2(etza)4].
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Synthesis of 5-aryl-1, 3, 4-oxadiazolyl-2-acetic acids.
Janda L.
Heterocyclic Communications, 7(5), 411-416 (2001)
A spontaneously resoluted zinc-organic framework with nonlinear optical and ferroelectric properties generated from tetrazolate-ethyl ester ligand.
Liang X-Q, et al.
CrystEngComm, 12(11), 3499-3501 (2010)
Kai-Fa Huang et al.
Protein expression and purification, 43(1), 65-72 (2005-08-09)
Glutaminyl cyclase (QC) catalyzes the N-terminal pyroglutamate formation of numerous hormones and peptides from their glutaminyl precursor. Pyroglutamate is a posttranslational or cotranslational modification important in many physiological and pathological processes. Here, we present the cloning of a QC cDNA
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