437018
N-Boc-1,6-己二胺 盐酸盐
97%
别名:
N-(6-氨基己基)氨基甲酸叔丁酯 盐酸盐, N-Boc-1,6-二氨基己烷 盐酸盐
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关于此项目
线性分子式:
(CH3)3COCONH(CH2)6NH2 · HCl
化学文摘社编号:
分子量:
252.78
Beilstein:
3631740
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
方案
97%
表单
solid
反应适用性
reagent type: cross-linking reagent
mp
162-164 °C (lit.)
官能团
Boc
amine
SMILES字符串
NCCCCCCNC(OC(C)(C)C)=O.[H]Cl
InChI
1S/C11H24N2O2.ClH/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12;/h4-9,12H2,1-3H3,(H,13,14);1H
InChI key
JSBWQIZQJOQPFN-UHFFFAOYSA-N
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应用
用于引入 C6 间隔臂的试剂。
N-Boc-1,6-hexanediamine hydrochloride is a general reagent to introduce a C6-spacer. It can be used in:
- Synthesis of poly(L-glutamic acid) gadolinium chelates as biodegradable MRI contrast agents.
- Synthesis of cholesteryl-functionalized hyaluronic acid-based anionic nanogel for protein delivery.
- Preparation of amphiphilic prodrug, containing anticancer drug chlorambucil, which would self-assemble to form micelles in aqueous solution.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Rational Design of an Amphiphilic Chlorambucil Prodrug Realizing Self-Assembled Micelles for Efficient Anticancer Therapy.
Hu X, et al.
ACS biomaterials science & engineering, 4(3), 973-980 (2018)
Synthesis and characterization of poly (L-glutamic acid) gadolinium chelate: a new biodegradable MRI contrast agent.
Wen X, et al.
Bioconjugate Chemistry, 15(6), 1408-1415 (2004)
Injectable hydrogel for sustained protein release by salt?induced association of hyaluronic acid nanogel.
Nakai T, et al.
Macromolecular Bioscience, 12(4), 475-483 (2012)
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