441279
(1R)-(-)-2-氮杂双环[2.2.1]庚-5-烯-3-酮
≥98%
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C6H7NO
化学文摘社编号:
分子量:
109.13
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
418-530-1
Beilstein/REAXYS Number:
4230721
MDL number:
Assay:
≥98%
Form:
solid
InChI key
DDUFYKNOXPZZIW-UHNVWZDZSA-N
InChI
1S/C6H7NO/c8-6-4-1-2-5(3-4)7-6/h1-2,4-5H,3H2,(H,7,8)/t4-,5+/m1/s1
SMILES string
O=C1N[C@@H]2C[C@H]1C=C2
assay
≥98%
form
solid
optical activity
[α]20/D −565°, c = 1 in chloroform
optical purity
ee: 99% (HPLC)
mp
94-97 °C (lit.)
Quality Level
General description
（1R）-（-）-2-氮杂双环[2.2.1]庚-5-烯-3-酮是一种双环γ -内酰胺。
Application
(1R)-(-)-2-氮杂双环[2.2.1]庚-5-烯-3-酮可用作制备以下物质的前体:
- 氨基帕拉米韦，其是一种强效神经氨糖酸苷酶抑制剂。
- 作为潜在的GABA氨基转移酶（GABA-AT）灭活剂的4-氨基-5-卤代戊酸的五元类似物。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
A new class of conformationally rigid analogues of 4-amino-5-halopentanoic acids, potent inactivators of ?-aminobutyric acid aminotransferase.
Qiu J and Silverman RB.
Journal of Medicinal Chemistry, 43(4), 706-720 (2000)
2-Azabicyclo [2.2. 1] hept-5-en-3-one: chemical profile of a versatile synthetic building block and its impact on the development of therapeutics.
Singh R and Vince R.
Chemical Reviews, 112(8), 4642-4686 (2012)
The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase
Bromba CM, et al.
Bioorganic & medicinal chemistry letters, 21(23), 7137-7141 (2011)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持