跳转至内容
Merck
CN

441287

(1S)-(+)-2-氮杂双环[2.2.1]庚-5-烯-3-酮

≥98%

登录 查看组织和合同定价。

选择尺寸


关于此项目

经验公式(希尔记法):
C6H7NO
化学文摘社编号:
分子量:
109.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
≥98%
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

(1S)-(+)-2-氮杂双环[2.2.1]庚-5-烯-3-酮, ≥98%

InChI

1S/C6H7NO/c8-6-4-1-2-5(3-4)7-6/h1-2,4-5H,3H2,(H,7,8)/t4-,5+/m0/s1

SMILES string

O=C1N[C@H]2C[C@@H]1C=C2

InChI key

DDUFYKNOXPZZIW-CRCLSJGQSA-N

assay

≥98%

optical activity

[α]20/D +565°, c = 1 in chloroform

optical purity

ee: 99% (HPLC)

mp

94-97 °C (lit.)

Quality Level

Application

这种内酰胺及其对映体是碳环核苷卡波韦对映异构体的前体。已证实 (-)-卡波韦是一种 HIV-1 强效抑制剂,根据临床试验可作为 AZT 的备选药。AZT 是 Wellcome Foundation Ltd. 的商标

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

R Vince et al.
Journal of medicinal chemistry, 33(1), 17-21 (1990-01-01)
(+-)-cis-[4-[(2,5-Diamino-6-chloropyrimidinyl)amino]-2- cyclopentenyl]carbinol (5a) was synthesized from 2-amino-4,6-dichloropyrimidine and cis-4-(hydroxymethyl)cyclopentenylamine (2a) by subsequent preparation of the 5-[(4-chlorophenyl)azo] derivative of the resulting pyrimidine (3a) and reduction of the azo moiety with zinc and acetic acid. The carbocyclic analogue of 2',3'-didehydro-2',3'-dideoxy 2-amino-6-chloropurine (6a)
Handa, S. et al.
Journal of the Chemical Society. Perkin Transactions 1, 1885-1885 (1994)
Campbell, J.A. et al.
The Journal of Organic Chemistry, 60, 4602-4602 (1995)
Jung. M.E. Rhee, H.
The Journal of Organic Chemistry, 59, 4719-4719 (1994)
E L White et al.
Biochemical and biophysical research communications, 161(2), 393-398 (1989-06-15)
Carbocylic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir; NSC 614846) is an antiretroviral agent which may be useful in the treatment of AIDS. We have synthesized the 5'-triphosphate of Carbovir and examined its ability to inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (EC

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持