Merck
CN
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文件

443271

Sigma-Aldrich

十二烯基丁二酸酐，异构体混合物

technical grade, 90%

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别名:
DDSA
经验公式（希尔记法）:
C16H26O3
CAS号:
26544-38-7
分子量:
266.38
EC 号:
247-781-6
MDL编号:
MFCD00036197
PubChem化学物质编号:
24868056
NACRES:
NA.23

等级

technical grade

质量水平

100

检测方案

90%

形式

liquid

折射率

n20/D 1.479 (lit.)

bp

150 °C/3 mmHg (lit.)

密度

1.005 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCC\C=C\C1CC(=O)OC1=O

InChI

1S/C16H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-13-15(17)19-16(14)18/h11-12,14H,2-10,13H2,1H3/b12-11+

InChI key

WVRNUXJQQFPNMN-VAWYXSNFSA-N

相关类别

一般描述

Dodecenylsuccinicanhydride (DDSA) is a mixture of isomers that belongs to the class of long-chained aliphatic anhydrides. It is composed of a dodecenyl (C12) chain attached to a succinic acid backbone and can undergo esterification, amidation, and ring-openingreactions. It is widely used as a cross-linking agent to synthesize hydrogels for drug delivery, coating for medical devices, and as a hardener for curing epoxy resins.

应用

Dodecenylsuccinic anhydride, mixture of isomers can be used:



  • As a precursor to synthesize modified chitosan hydrogels useful for the sustained local delivery of drugs. This modification enhances the hydrophobicity of chitosan, allowing it to better encapsulate and retain hydrophobic drugs.
  • To prepare high-performance Arabinoglucuronoxylan (AGX)-based biosurfactants using rapid homogeneous esterification reactions. These surfactants can be used for oily sludge remediation and oil recovery.
  • As a hardener for curing thermosetting epoxy resins used in various fields such as paints, corrosion protective coatings, adhesives, and electrical circuits.
  • As a modifying agent to prepare collagen hydrogels to fabricate skin wound dressings.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317 - H319 - H413

危险分类

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Jeanette Bannoehr et al.
PloS one, 15(3), e0225901-e0225901 (2020-03-03)
Hereditary nasal parakeratosis (HNPK) is an inherited disorder described in Labrador Retrievers and Greyhounds. It has been associated with breed-specific variants in the SUV39H2 gene encoding a histone 3 methyltransferase involved in epigenetic silencing. Formalin-fixed biopsies of the nasal planum
Experimental study on the surface properties of nanoalumina-filled epoxy resin nanocomposites
Deesy Pinto, et al.
Applied Sciences, 10, 733-733 (2020)
Dodecenylsuccinic anhydride modified collagen hydrogels loaded with simvastatin as skin wound dressings
Christian E Olivetti, et al.
Journal of Biomedical Materials Research Part A, 107, 1999-2012 (2019)
A A Gorkun et al.
Biomedical materials (Bristol, England), 13(4), 044108-044108 (2018-05-04)
One of the essential goals in regenerative medicine is microvascularization which enables an effective blood supply within de novo constructed tissues and organs. In our study, we used two common multipotent mesenchymal stromal cell (MMSC) sources (subcutaneous adipose tissue and
Dodecenylsuccinic anhydride modified chitosan hydrogels for the sustained delivery of hydrophobic drugs. The case of thymol buccal delivery
Alvarez Echazu, et al.
Journal of Applied Polymer Science, 139, 51432-51432 (2022)
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