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关于此项目
线性分子式:
ClC6H3(OCH3)CONHCH2C6H4SO2NH2
化学文摘社编号:
分子量:
368.84
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
240-722-5
MDL number:
Assay:
95%
Quality Level
assay
95%
mp
209-214 °C (lit.)
functional group
amide, chloro
SMILES string
COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(N)(=O)=O
InChI
1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22)
InChI key
KVWWTCSJLGHLRM-UHFFFAOYSA-N
General description
5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide is an organic building block. It has been reported as an intermediate in the synthesis of glyburide. Synthesis of 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide has been reported.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways
Trendelenburg G.
Journal of Cerebral Blood Flow and Metabolism (2014)
Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction.
Takahashi M.
International Heart Journal, 55(4), 380-380 (2014)
Carlo Marchetti et al.
Journal of cardiovascular pharmacology, 63(4), 316-322 (2013-12-18)
The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitro but requires very high doses in vivo, associated with hypoglycemia. The aim
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 463442-5G | 04061832355375 |